UNIVERSITAS AIRLANGGA



Detail Article

Veterinaria Medika

ISSN 1979-1305

Vol. 8 / No. 2 / Published : 2015-07

Order : 12, and page :193 - 198

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Original Article :

The effect of mangosteen peel extract (garcinia mangostana l.) to the number of placental trophoblast cells in mice (mus musculus) exposure to cigarette smoke

Author :

  1. Cristianita M. Tany*1
  2. Widjiati*2
  3. Sri Pantja Madyawati*3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

The purpose of this study was to find out the effect of mangosteen peel extract (Garcinia mangostana L.) to the number of placental trophoblast cells in mice (Mus musculus) exposure to cigarette smoke. Experimental animals were used 25 pregnant mice strain Balb / c, and then divided into five groups K-, K+, P1, P2, and P3. K- was only given distilled water during day 6 to day 17 of gestation, K + was given exposure to cigarette smoke during day 6 to day 17 of gestation, P1, P2, and P3 were exposured to cigarette smoke and given mangosteen peel extract at a dose of 50 mg / kg body weight, 100 mg / kg body weight, 150 mg / kg body weight during gestation day 6 to day 17. The sample used in this study was 25 plasenta. Data were analyzed using ANOVA and Tukey test. The results showed significant differences in the number of placental trophoblast cells of mice between treatment groups. According to research results, a dose of 100- 150 mg / kg BW has a large effect on the reduction in the number of placental trophoblast cell death and had the optimum dose to inhibit the placental trophoblast cell death.

Keyword :

Garcinia mangostana L., placental trophoblast cells, cigarette smoke,


References :

Chomnawang, M.T., S.Surassmo., V.S. Nukoolkarn and W.Gritsanapan,(2007) Effect of Garcinia mangostana on Inflammation Caused by Propionibacteriumacnes 78: 401–8 : Fitoterapia

Kaihena, M., Syamsu., Y. Yasir and M. Hatta,(2015) The effect of the petroleum ether extracts from mangosteen pericarp (Garcinia mangostana L.) on interferon-gammaand, interleukin-12 activities in albino wistar rats (Rattus norvegicus) Infected with Mycobacterium tuberculosis 3 (1): 8- 13 : American Journal of Microbiological Research

Sie, J.,(2013) Daya Antioksidan Ekstrak Etanol Kulit Buah Manggis (Garsinia mangostana L.) Hasil Pengadukan Dan Reflux 2 (1) : Jurnal Ilmiah. Universitas Surabaya

Widjiati, S.E. Pusporini dan A.M. Zainal,(2012) Perbandingan Angka Fertilitas dan Hambatan Perkembangan Embrio Mencit yang Dikultur dalam Medium M16 dan Human Tubal Fluid 13 (3) : 227-234 : Jurnal Veteriner





Archive Article

Cover Media Content

Volume : 8 / No. : 2 / Pub. : 2015-07
  1. The Effect Of Acupuncture On Sodium, Potassium, And Chloride Blood Plasma In Thoroughbred Horse After Exercise
  2. The Effects Of Insulin Transferin Selenium (its) Supplementation On Embryo Freezing Media At Morula Stage Towards The Percentage Of Embryonic Development At Blastula Stage
  3. The Liver Histopathology Of Mice (mus Musculus) Cause Exposure Carbofuran Insectiside
  4. Effect Of Mangosteen Rind Extract (garcinia Mangostana L.) To Necrosis Alveolar Type Ii Cell Of Lungonpregnant Mice (mus Musculus)exposured By Cigarette Smoke
  5. Histopathological Appearance Of Gastrointestinal Tract Iv Instar Mosquito Larvae Of Aedes Aegypti After Dipping With Active Compounds Of Permot Leaf Extract (passiflora Foetida Linn.) And Its Potential As Bioinsecticide
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  7. The Seminal Plasma Protein Of Cow Sustain Quality Of Beans Goat Spermatozoa After Equilibration In Freezing Process
  8. The Potential Of Garlic (allium Sativum) Infuse To Caecum Of Broilers Histopathology Infected By Escherichia Coli
  9. The Effectiveness Of Giving Haemopoetic Stem Cells In The Pregnant Mice (mus Musculus) Exposed To Plumbum Towards The Decreasing Number Of Necrocis Cells And Expression Of Caspase-3 In Placenta
  10. Protective Effect Of Binahong Leaf Extract [anredera Cordifolia (ten.) Steenis] To Renal Histopathological Of Rat (rattus Norvegicus) Induced With Borax (na2b4o710h2o)
  11. Effect Of Antibacterial Traditional Apple Vinegar And Apple Vinegar Products On The Growth Of Staphylococcus Aureus In Vitro
  12. The Effect Of Mangosteen Peel Extract (garcinia Mangostana L.) To The Number Of Placental Trophoblast Cells In Mice (mus Musculus) Exposure To Cigarette Smoke
  13. Analysis Of Humoral Immune Response (igg) In Rabbit Immunized With Proteins Of Leucocytozoon Caulleryi
  14. Isolation Of Methicillin-resistant Staphylococcus Aureus (mrsa) In Dog Nasal Swab With Oxacillin Screen Agar Confirmation Test
  15. Effect Of Prostaglandin F2α, Pregnant Mare Serum Gonadotropin, And A Combination Of Pregnant Mare Serum Gonadotropin And Human Chorionic Gonadotropin On Pregnancy Rates And Litter Size Of Mice
  16. Through The Provision Of Drinking Water Multiprobio Against Performan Broiler Chicken Production