Catalog :



Detail Article

Majalah Farmasi Airlangga (Airlangga Journal of Pharmacy)

ISSN : 0852-1050

Vol. 4 / No. 2 / Published : 2004-08

Related with : Scholar   Yahoo!   Bing

Original Article :

Pengaruh Jenis Humektan Terhadap Pelepasan Asam Sitrat dari Basis Gel Secara In Vitro.

Pengaruh Jenis Humektan Terhadap Pelepasan Asam Sitrat dari Basis Gel Secara In Vitro.

Author :

  1. Widji Soeratri --> Bagian Farmasetika Fakultas Farmasi Universitas Airlangga
  2. Noorma Rosita --> Bagian Farmasetika Fakultas Farmasi Universitas Airlangga
  3. Ekarina Ratna Himawati --> Bagian Farmasetika Fakultas Farmasi Universitas Airlangga

Abstract :

The study of skin whitening products effectiveness has been conducted. The products contained citric acid as whitening agent, and formulated in gel bases with three different humectants,i.e. propylene glycol, sorbitol, and glycerol, respectively. In spite of their performances, viscosity,and pH, the release of citric acid from the gel was also determined as a parameter of their effectiveness. These were performed with modificated instrument of Transdermal Delivery System Apparatus (USP 23). Analysis of the data was performed by Higuchi’s formula, and then the coefficient permeability on the gel base with different humectant were calculated. The result showed that the flux value of citric acid release and the cellophane membrane coefficient permeability of citric acid from the gels containing glycerol were the highest, followed with those containing propylene glycol and sorbitol respectively.

Keyword :

humektan, asam sitrat,


Daftar Pustaka :

  1. H.C. Ansel, (1989). Introduction of Pharmaceutical Dosage Form, 4th Edition. New York : Lea & Febiger
  2. M.S. Balsam, (1972). Cosmetics Science and Technology, 2nd Edition, Vol. 1. Canada : Willey & Sons
  3. E. Sagarin, (1972). Cosmetics Science and Technology, 2nd Edition, Vol. 1. Canada : Willey
  4. B. Idson, (1995). Treatment Cosmetics II Retinoid and AHAs, Drug & Cosmetics Industry. :
  5. H. Kenneth, (1990). Official methods of Analyse of The Association of Official Analytical Chemistry, 15th Ed.. Virginia : Association of Official Analytical Chemistry
  6. L. Lachman, (1994). Teori dan Praktek Farmasi Industri,Edisi ketiga. Jakarta : Indonesia University Press
  7. H.A. Lieberman, (1994). Teori dan Praktek Farmasi Industri,Edisi ketiga. Jakarta : Indonesia University Press
  8. J.L. Kanig, (1994). Teori dan Praktek Farmasi Industri,Edisi ketiga. Jakarta : Indonesia University Press
  9. M. Tilar, (2000). Pemanfaatan produk Pemutih Untuk Meningkatkan Penampilan dan Percaya Diri. Surabay : Seminar Sehari LEM Fakultas Farmasi Universitas Airlangga
  10. R.G. Harry, (1982). Harry’s Cosmeticology, Chem. Publication Co. Inc, 7th Edition. New York : Chem. Publication Co.
  11. Widji Soeratri, (1996). Studi in Vitro Pelepasan Asam--hidroksi 1,2,3 propanatrikarboksilat dalam Basis Krim, Lotio dan Gel. : Kongres Nasional ISFI
  12. Umul Jariah, (1996). Studi in Vitro Pelepasan Asam--hidroksi 1,2,3 propanatrikarboksilat dalam Basis Krim, Lotio dan Gel. : Kongres Nasional ISFI


   


Archive Article

Cover Media Content

Volume : / No. : / Pub. :