UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 49 / No. 3 / Published : 2013-07

Order : 11, and page :186 - 192

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Original Article :

Pharmaceutical care and anti-hypertension treatment at trf-ht patients undergoing regular hemodialysis. a study at hemodialysis room, dr haryoto hospital, lumajang, east java, indonesia

Author :

  1. Sri Any Sulistyowati*1
  2. Budi Suprapti*2
  3. Benny Gufron*3
  1. Department of Clinical Pharmacy, Faculty of Pharmacy, Airlangga University, Surabaya
  2. Dosen Fakultas Farmasi
  3. Dr Haryoto Hospital, Lumajang

Abstract :

Pharmaceutical care is important for patients who received drug therapy, especially patients with terminal renal failure withhypertension (TRF-HT) who underwent hemodialysis. Pathophysiological conditions of HT patients and usage of anti-hypertensivemedications (AHT) is a combination that raises potential problems related to drug (DRPs). The purpose of the study was to assessthe types of DRPs TRF-HT in patients undergoing HD and assessed PC intervention and interventions received doctor, nurses, andpatients. This study was prospective observational cohort analytic type. Each patient underwent TRF-HT regular HD would beaccompanied by the intervension of the PC and AHT medication for 8 weeks. Samples were taken by 36 TRF-HT patients who gotintervension of PC every undergoing HD. HD frequency maximum of 2 times per week. Discovered 275 DRPs with the majority ofpatients can experience >1 DRPs related AHT drug. Classification and percentage of DRPs according to the American Society ofHealth-System Pharmacist (AHSP) 1998 is as follows: untreated indication 4%, 3% improper drug selection, sub therapeutic dosage1%, failure to receive medication 27%, overdosage 4%, adverse drug side reaction (ESO) 37%, drug interaction 24%, medicationuse without indication 0%. One hundred of PC intervention doctor with details of consultation 75%, communication 9%, andsuggestions 16%. PC intervention in patients or families patients in form counseling information education as much as 219 times,84% IEC accepted. TRF-HT patients who underwent regular HD and administration of AHT potentially experiencing DRPs and PCimproves drug therapy appropriately.(FMI 2013;49:186-192)

Keyword :

hemodialysis, antihypertension drugs, pharmaceutical care, DRPs,


References :

Agarwal R,(2010) Blood pressure and mortality among hemodialysis patients - : Hypertension

Ashley C and Currie A,(2009) The Renal Drug Handbook, 3rd ed. Buckinghamshire : Radcliffe Publishing





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