Majalah Biomorfologi
ISSN 0215-8833
Vol. 26 / No. 1 / Published : 2013-01
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Original Article :
Deteksi kelainan cns melalui kelainan septum pellucidum
Author :
- Sakina*1
- Viskasari Pintoko Kalanjati*2
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Abstract :
Septum pellucidum is a midline structure between two cerebral hemisphere. It separates the two lateral ventricles. The development of this structure is correlated to brain development. The abnormalities of septum pellucidum, such as agenesis septum pellucidum and cavum septum pellucidum, are usually associated with other CNS anomalies. Agenesis septum pellucidum is relatively rare, estimated to occur in 2-3 per 100.000 births. However, this abnormality is closely associated with the occurrence of grave neuromorbidities i.e. holoprosencephaly, septo-optic dysplasia, malformation of corpus callosum, and chiari malformation type 2, ventriculomegaly, hippocampal displasia, cerebral cortex displasia, and displasia of optic nerves; whilst abnormality of cavum septum pellucidum is associated to schizophrenia and anti-social personality. The American Institute of Ultrasound in Medicine and American College of Radiology recommends septum pellucidum as one of regular check-up required in the antepartum sonography. It is suggested that the septum pellucidum examination in antenatal care in Indonesia is conducted so that an early treatment plans can be made.
Keyword :
Septum pellucidum, CNS malformation,
References :
Barkovich, A.J. & Norman D.,(1988) Absence of the septum pellucidum: a useful sign in the diagnosis of congenital brain malformations - : American Journal of Radiology
Bault, J.P. Salomon, L.J. Guiband, L. & Achiron, R.,(2011) Role of three-dimensional ultrasound measurement of the optic tract in fetuses with agenesis of the septum pellucidum - : Ultrasound Obstetric Gynecology
Brown, A.S. et al.,(2009) Prenatal infection and cavum septum pellucidum in adult schizophrenia - : Schizophr Res
Chun, Y.K., Kim, H.S., Hong, S.R. & Chi, J.G.,(2010) Absence of the septum pellucidum associated with a midline fornical nodule and ventriculomegaly: a report of two cases. - : Journal Korean Med Sci.
Li, Y. et al.,(2011) Outcome of fetuses with cerebral ventriculomegaly and septum pellucidum leaflet abnormalities - : American Journal of Radiology
Archive Article
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 Volume : 26 / No. : 1 / Pub. : 2013-01 |
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