Majalah Biomorfologi
ISSN 0215-8833
Vol. 19 / No. 1 / Published : 2006-01
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Original Article :
Pengaruh infusa mengkudu ( morinda citrifolia ) terhadap histopatologi ginjal mencit ( mus musculus ) setelah pemberian pakan tinggi lemak
Author :
- Eka Hestianah*1
- -
Abstract :
The purpose of the research is find out the effect of administration of Morinda citrifolia infusion to histological changes of mices kidney after the high fat intake.Twenty five male mices with average weight 30 gram devided into five groups. Group I is negative controle (PO-), got the standard feeding + 1ml aguadest. Group II is positive control ( PO+ ), got the high fat intake + 1 ml aguadest. The others are treatment groups including : P1, P2, P3 got high fat intake and 20%, 40%, 60% Morinda citrifolia infusion. After 30 days of the treatment mices were sacrificed and made the H. E staining histological preparation of the mices kidney. Data analyses followed by H test and Wilcoxon’s Rank Sum Test.The result followed : PO+, P1 showed the most severe cloudy swelling and glomerular enlargement, P2, P3 showed the severest medullary interstitial renal bleeding, PO-, P3 showed the mildest cortex interstitial renal bleeding.
Keyword :
Morindra citrifolia infusion, histopathology of mices kidney,
References :
Sjabana D,(2002) Pesona Tradisional dan Ilmiah Mengkudu Morinda
citrifolia. Edisi Kesatu. , . Jakarta : Penerbit Salemba Medika
Ramadhani RB,(2002) Pesona Tradisional dan Ilmiah Mengkudu Morinda
citrifolia. Edisi Kesatu. , . Jakarta : Penerbit Salemba Medika
Gustin. E S,(2003) Pengaruh Infusa Mengkudu ( Morinda citrifolia ) Terhadap kadar
Trigliseria, Kolesterol Total, LDL dan HDL serum darah mencit ( Mus musculus )
Setelah Pemberian Pakan Tinggi Lemak. Surabaya.
Lu, FC. 1995. Surabaya : Fak. Ked. Hewan. Unair.
Archive Article
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 Volume : 19 / No. : 1 / Pub. : 2006-01 |
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