Majalah Biomorfologi
ISSN 0215-8833
Vol. 19 / No. 1 / Published : 2006-01
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Original Article :
Pengaruh pemberian pb asetat peroral terhadap diameter serat saraf dan akson n.ischiadicus tikus putih (rattus norvegicus)
Author :
- Ulfa Elfiah*1
- Laboratorium Anatomi
Program Studi Pendidikan Dokter
Universitas Jember
Abstract :
This research showed the oral administration of lead acetate to rats could affect diameter of myelinated fibres and axon of N.Ischiadicus. The post test only control group design was used in this research. 30 male rats were divided into five groups of treatment. Aquadest was administered to group I (K1). Lead acetate with doses : 65, 125, 250 and 500 mg/kgbw were adminestered to group II, III, IV and V. Lead acetate in rats were exposed for 10 weeks and then made histological preparation from N.Ischiadicus with osmic acid as fixation and toloidin blue as staining. The result of this research proved that oral administration of lead acetate affected diameter of myeilinated fibres with p0,05).
Keyword :
diameter of myelinated fibres, diameter of axon, lead acetate oral dosing,
References :
M Zainudin,(1998) Metodologi Penelitian Surabaya : Universitas Airlangga
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