UNIVERSITAS AIRLANGGA



Detail Article

Journal Of Emergency

ISSN 2301-7864

Vol. 3 / No. 1 / Published : 2014-06

Order : 7, and page :45 - 49

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Original Article :

Clinical and laboratory profiles relationships of preeclampsia-eclampsia patients with maternal mortality in the dr. soetomo hospital surabaya

Author :

  1. Selamat*1
  2. Aditiawarman*2
  1. Mahasiswa Fakultas Kedokteran
  2. Dosen Fakultas Kedokteran

Abstract :

Background : Preeclampsia-eclampsia is one of the most common complications of pregnancy and one of the highest causes of maternal mortality (15-20%) in developing countries. Preeclampsia-eclampsia and high maternal mortality rate in Indonesia is a phenomenon that can not be separated, as known three biggest cause of maternal mortality is preeclampsia-eclampsia, infection and bleeding after childbirth has lasted more than 30 years. The most common cause of maternal death in the case of pre-eclampsia HELLP syndrome (hemolysis, elevated liver enzymes and low platelets) and pulmonary edema.   Objective: to study the relationship between clinical and laboratory profiles of preeclampsia – eclampsia patients with incidence of maternal mortality.   Methods : This study is a retrospective observational analytic studies in patients with preeclampsia-eclampsia were treated in Dr. Soetomo hospitals  between periode January 2009 to December 2011. Data were retrieved from Dr.Soetomo Hospital Surabaya medical records. Variables that was going to be assessed were clinical conditions (pulmonary edema, cerebral edema, intracerebral hemorrhage, HELLP syndrome, DIC, renal failure and retinal detachment) and laboratory (hemoglobin, leukocytes, hematocrit, platelets, GDA, SGOT, SGPT, BUN, SK, Na , K, albumin, LDH) and the outcomes (alive or dead). Data were processed using SPSS software. On each of the variables logistic regression test was performed.   Result : During the 3-year period were found 247 cases of preeclampsia-eclampsia with maternal mortality rate  10.5%. ALT> 40 U/L (p=0.001) and Platelets count <150.000 /μL (p=0.0001) had a significant relationship with the incidence of maternal mortality in HELLP syndrome. Creatinine serum > 1.2 mg/dL (p=0.0001) had a significant relationship with the incidence of maternal mortality in ARF. Pulmonary edema had a significant relationship with the incidence of maternal mortality (p=0.0001). Platelets count <150000 /μL had a significant relationship with the incidence of maternal death in cerebral edema (p=0.0001).   Summary : This research objective is to study the relationship between clinical and laboratory profiles in preeclampsia-eclampsia patients who died in Dr.Soetomo hospital Surabaya.

Keyword :

Preeclampsia, eclampsia, laboratory results, maternal mortality,


References :

Cunningham GF,(2010) Hypertensive Disorder in Pregnancy. in William Obstetric 23rd Edition 764-78 : William Obstetric





Archive Article

Cover Media Content

Volume : 3 / No. : 1 / Pub. : 2014-06
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  5. Intraperitoneal Adhesion Prevention With An Intramuscular Injection Of Diphenhydramine Perioperative
  6. Blood Pressure And Pulse Rate Of Severe Preeclampsia S Receiving Magnesium Sulfate And Undergoing Cesarean Section Under General Anesthesia
  7. Clinical And Laboratory Profiles Relationships Of Preeclampsia-eclampsia Patients With Maternal Mortality In The Dr. Soetomo Hospital Surabaya
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