UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 50 / No. 3 / Published : 2014-07

Order : 11, and page :191 - 196

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Original Article :

Analysis of complicated factors affecting therapy effectiveness in urinary tract infections

Author :

  1. Mirza Junando*1
  2. Achmad Taruna*2
  3. Didik Hasmono*3
  1. Department of Pharmacy, Dr. H. Abdul Moeloek Hospital, Lampung
  2. Nephrology and Hipertension Division, Internal Departemen, Dr. H. Abdul Moeloek Hospital, Lampung
  3. Dosen Fakultas Farmasi

Abstract :

Based on host factors and bacterial causes of infection, urinary tract infection (UTI) can be divided into complicated andnoncomplicated UTI. Complicated UTI are infection with structural and functional urinary tract abnormality, or infection withcomorbid conditions that may extend the therapeutic time and have a high risk of treatment failure, such as UTI with indwellingurinary catheter, chronic kidney disease and diabetes mellitus. This study was to determine antibiotics susceptibility pattern ofisolated microorganism from UTI and to analyze the impact of complicated factor on UTI therapy effectiveness associated withpatient’s clinical and laboratory response. This study was a descriptive analytic observational cohort-prospective study conducted atDr. H. Abdul Moeloek Hospital, Lampung, from November 2013 to January 2014. The mid stream urine specimens of initiallyhospitalization patients were collected based on urinalysis result for bacterial culture and antibiotics susceptibility test according toCLSI. Clinical and laboratory response improvements were assessed since the first admission day and until the patient improved.Thirty five patients with complicated UTI were sampled, but only thirty met the inclusion criteria. Whereas, five patients’ bacteriadata, which cause infection and antibiotical susceptibility, were still taken. The most frequently isolated gram-negative bacteria wasEschericia coli (37%) and gram-positive bacteria was Staphylococcus sp. (11%). In conclusion, antibiotics with the potential of morethan 60% are amoxicillin-clavulanic acid, amikacin and meropenem. There was no significance effect between single complicatedUTI; between single and combined complicated UTI with therapeutic effectiveness (p > 0,05). (FMI 2014;50:191-196)

Keyword :

Complicated urinary tract infection, urinary cathether, diabetes mellitus, chronic kidney disease, amoxycillin-clavulanic acid,


References :

Hooton TM,(2000) Pathogenesis of urinary tract infections: an update 46, 1-7 : J Antimicrob Chemother

Samirah, Darwati, Windarwati, Hardjoeno,(2006) Pola dan sensitivitas kuman di penderita infeksi saluran kemih 12, 110-113 : Ind Jour of Clin Path and Med Lab





Archive Article

Cover Media Content

Volume : 50 / No. : 3 / Pub. : 2014-07
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  2. Detection Of Gyra Gene Mutation Region In Fluoroquinolone Resistant Mycobacterium Tuberculosis Isolate From Surabaya Indonesia
  3. Intravenous Vitamin C Administration Decreases Nitric Oxide Serum Level In Severe Burn Injury
  4. The Overview Of Macrophage, Mast Cell, And Lymphocyte Activity In The Efficacy Distinction Of Pain Reduction For Dry And Wet Cupping Therapies
  5. Effectiveness Of Fosfomycin On Prevention Of Surgical Site Infection Of Closed Brain Injury Patients After Craniotomy In Emergency Unit Dr. Soetomo Hospital
  6. Soot Particulate Matter Exposure Increases Interleukin 6 Levels In The Mechanism Of Cardiovascular Disorders
  7. Electric Shock Increases Vcam And Mcp In Mice Endothelial Blood Vessel
  8. Magnesium And Potassium Parenteral Supplementation Does Not Produce Significant Effect On Magnesium And Potassium Serum Level Of Cervical Cancer Patients Receiving Cisplatin Chemotherapy
  9. Effect Of G-csf On Anc Level In All (acute Lymphoblastic Leukemia) Patient With Neutropenia And Febrile Neutropenia During Chemotherapy
  10. Comparative Effectiveness Of Paracetamol And Metamizol As Antipyretics In Patients With Moderate And Severe Brain Injury In Dr. Soetomo Hospital, Surabaya
  11. Analysis Of Complicated Factors Affecting Therapy Effectiveness In Urinary Tract Infections
  12. In Infant With Acute Diarrhea, Nutritional Status Has Correlation With Dehydration Degree, But Not With Mother’s Education And Breastfeeding
  13. The Use Of Antibiotics In Patients With Urinary Tract Infection

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