Folia Medica Indonesiana
ISSN 0303-7932
Vol. 48 / No. 4 / Published : 2012-10
Order : 1, and page :144 - 149
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Original Article :
Antibacterial activity of belimbing wuluh (averrhoa bilimbi linn) extract on salmonella typhi growth
Author :
- Fitria Hasdiana*1
- Sutji Kuswarini*2
- Eko Budi Koendhari*3
- Mahasiswa Fakultas Kedokteran
- Dosen Fakultas Kedokteran
- Dosen Fakultas Kedokteran
Abstract :
Typhoid fever is an endemic disease which still have high incidence rate especially in developing countries like Indonesia. Typhoid fever is caused by Salmonella typhi. Starfruit (Averrhoa bilimbi Linn) leaf extract has antibacterial capability against some strains of bacteria. Therefore, researchers examined the use of starfruit leaf extract against Salmonella thypi bacteria. This was a true experimental research that test the antibacterial activity of the starfruit (Averrhoa bilimbi Linn) leaf extract against Salmonella typhi growth. This research using diffusion method on Muller Hinton Agar Palte. Starfruit leaf extracted with ethanol and divided in several concentrations. Statistical tests is conducted with descriptive test and Kruskal Wallis test to compare antibacterial effect of starfruit leaf extract in different concentrations in Salmonella thypi. Mean diameter of the inhibition on Salmonella typhi antibacterial activity test were as follows : Treatment 1 (0.3 g/ml) = 20.75 mm; Treatment 2 (0.4 g/ml) = 21.88 mm; Treatment 3 (0, 5 g/ml) = 22.88 mm; Control 1 (chloramphenicol 30 mcg) = 30 mm; Control 2 (5% DMSO) = 0 mm. Based on the obtained results, qualitatively it can be concluded that the concentration of starfruit (Averrhoa bilimbi Linn) leaf extract gave growth inhibition zone in Salmonella typhi at concentrations of 0.3 g/ml, 0.4 g/ml and 0.5 g/ml. Based on the standard Clinical Laboratory Standard Institute (2008), all of them provide a sensitive response to inhibit the growth of Salmonella typhi as well as giving antibiotic chloramphenicol as control. (FMI 2012;48:144-149)
Keyword :
Salmonella typhi, Averrhoa bilimbi Linn leaf, antibacterial, diffusion,
References :
Robinson T,(1991) The Organic Constituents of High Plant, 4th ed New York : University of Massachusetts
Sampurno,(2000) Parameter Standar Umum Ekstrak Tumbuhan Obat Jakarta : Departemen Kesehatan
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