UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 46 / No. 2 / Published : 2010-04

Order : 9, and page :139 - 145

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Original Article :

Association between heart disease in pregnancy with cardiac events

Author :

  1. Suryono *1
  2. Jatno Karyono*2
  1. Department of Cardiology and Vascular Medicine, Faculty of Medicine, Airlangga University, Dr Soetomo Teaching Hospital Surabaya
  2. Department of Cardiology and Vascular Medicine, Faculty of Medicine, Airlangga University, Dr Soetomo Teaching Hospital Surabaya

Abstract :

Pregnancy in heart disease is at high risk for cardiac events. Heart failure (NYHA III-IV), ejection fraction (EF)<40%, cyanocis and left ventricle obstruction (MVA< 2 cm2 or AVA <1,5 cm2) are parameters that still use in predicting cardic events in pregnancy. But in clinical experience, pregnancy with MVA 1.5-2 cm2 still can have the pregnancy without cardiac events. These parameters haven’t included congenital heart disease (CHD) and hypertension with preserved EF and cyanosis hadn’t still occured has the potency the occurance of cardiac events. To date, no exact parameters associate with severity of CHD are high risk for occurance cardiac events in pregnancy. The objective was to prove MVA <1.5cm2, CHD with PASP 60 > mmHg, and chronic hypertension with left ventricle hypertrophy as risk of occurance for cardiac events in pregnancy. Ninety two pregnant women with mitral stenosis, MVA < 1.5cm2, CHD with PASP >60 mmHg and chronic hypertension with left venricle hypertrophy based on registry from 2002 to 2007, restropectively through medical record and classified into groups based on occurance of cardiac events. Ninety two pregnant women in 5.5 year period fulfilled inclusion criterias. 46.75% had cardiac events. There are significant association between MVA <1.5cm2 (CI 1.61-78.56, p=0.01), CHD with PASP > 60 mmHg (CI 1.97-19.04, p=0.01) and chronic hypertension with left ventricle hypertrophy (CI 1.16-52.35, p=0.001) with the occurance of cardiac events. In conclusion, pregnancy with severe MS, CHD with pulmonary hypertension moderate-severe and chronic hypertension with left ventricle hypertrophy are at risk of cardiac events along the pregnancy.

Keyword :

pregnancy, heart disease, cardiac events,


References :

Alpert, JS & Ewy, GA,(2002) Manual of Cardiovascular Diagnosis and Therapy, 5th edn Philadelphia : Lippincott Williams & Wilkins

Bonow, RO & Braunwald, E,(2005) Valvular heart disease, in DP Zipes, P Libby, RO Bonow & E Braunwald (eds), Heart Disease: A texbook of cardiovascular medicine, 7th edn - : Elsevier Saunders

De Swiet, M,(1997) Hypertension and pre-eclamptic toxaemia, in C Oakley (ed.), Heart disease in Pregnancy London : BMJ Publishing Group





Archive Article

Cover Media Content

Volume : 46 / No. : 2 / Pub. : 2010-04
  1. Polymorphism Of Natural-resistance-associated Macrophage Protein 1 (nramp1) D543n Gene And Expression Of Nramp1 On Lung Tuberculosis Patients And Nurses In Surabaya
  2. 45 Kda Fimbria Protein Of Proteus Mirabilis As Hemagglutinin And Adhesion Protein
  3. Diagnostic Value Of Widal Slide Assay Using One Phage Type Local Antigen Compared With Four Phage Types Local Antigen In Typhoid Fever Patients In Surabaya
  4. Differences Of Tumor Necrosis Factor Alpha (tnf-α) Plasma Concentration In Malaria Patients With Anemia And Without Anemia
  5. Differences Of Epidermal Growth Factor (egf) Concentration Between Unpreserved And Preserved Amniotic Membrane
  6. Cytotoxicity Effect Of Curcuma Aeruginosa Extract On Fibroblast With Mtt Assay Method
  7. Correlation Between Blood Serotonin Level With Consciousness Level And Depression Symptoms In Moderate Brain Injury Patients
  8. Blood Serotonin Level With Depression Situation And Neurocognitive As A Reflection Of Neuron Condition In Six Months After Moderate Brain Injury
  9. Association Between Heart Disease In Pregnancy With Cardiac Events
  10. Endoscopic Finding Of Upper Gastrointesinal Bleeding At Dr Soetomo Hospital, Surabaya
  11. Correlation Between Tnf-α, Il-1β, Pge2 And Spla2 Levels With Severity Of Dengue Hemorrhagic Fever
  12. Case Report: Auditory Neuropathy In Dr. Soetomo Hospital

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