UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 49 / No. 2 / Published : 2013-04

Order : 9, and page :112 - 115

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Original Article :

Bmd-qus assessment result appropriates to diagnose osteoporosis

Author :

  1. Priyambada C Nugraha*1
  2. Rachmat G Wachjudi*2
  3. Tati R Mengko*3
  1. Medical-electronic Engineering Department, Health Polytechnique, Surabaya
  2. Reumathologi Division, Internal Medicine Department, Padjadjaran University, Bandung
  3. Biomedical Engineering, Electrical Engineering Department, ITB, Bandung

Abstract :

A medical equipment with ultrasound-wave technology, which is called Quantitative Ultrasound (QUS), is readily available tomeasure bone mass/mineral density (BMD) as a tool in diagnosing osteoporosis. This equipment measures the quantity ofultrasound-wave that passes through heel-bone (calcaneus). The measurement results are expressed in T-score and Z-score. Thecharacteristics of QUS are simple, save, and cheap, but the output result is not accurate. WHO’s “gold standard” for BMDmeasurement is Dual-energy X-ray Absorbtiometry (DXA). Up to now, in Indonesia DXA has been available only at Jakarta. Butassessment cost of DXA is relatively expensive for Indonesian people. Moreover, QUS and DXA use Japanese woman bone as thereference. Statistical analysis of 15 parallel assessment results from QUS-DXA is done to get correlation coefficient andmathematical equation between two assessment results. T-scores from QUS are correlated to gr/cm2 and T-scores from DXA of FN(femoral-neck), LS (lumbar-spine) and RD (radius). Z-scores from QUS are correlated to Z-scores from DXA of FN, LS and RD.Statistical analysis is also done to 132 QUS T-score data from woman population with peak bone mass age, in order to getpopulation T-score mean value. QUS assessment results are correlated to DXA assessment results at three sites with meancorrelation coefficient of 0.67. The mean of correlation coefficient got from DXA assessment results at three measurement sites is0.81. Moreover, QUS assessment result is combined and adjusted into this correlation equation, to get DXA data estimation. Themean value of T-score resulted by the reference data analysis is –1 (minus one). This value is then used as a correction factor of theprevious/original QUS reference equation, so that we can have local reference equation and local criterion. QUS-DXA correlationequation is an answer for the rare and expensive DXA assessment. Furthermore, local reference equation and local criterion areseveral ways to increase QUS accuracy as the bone mass/mineral density measurement tool. Hopefully, this research will increasethe optimality of QUS assessment result during the process of diagnosing. Next, the accuracy of diagnosis will increase theeffectiveness & efficiency of therapy, and finally it will raise the quality of public health service. (FMI 2013;49:112-115)

Keyword :

bone mass/mineral density, quantitative ultrasound, assessment result, statistical analysis, reference,


References :

Fogelman I and Blake GM,(2000) Different approaches to bone densitometry - : J Nucl Med

Francis RM,(1990) Osteoporosis: Pathogenesis and Management London : Kluwer Academic Publisher





Archive Article

Cover Media Content

Volume : 49 / No. : 2 / Pub. : 2013-04
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  4. Maternally Inherited Nucleotide Variation Of Mitochondrial Dna (mtdna) D-loop Region 126 Pb (nt: 34-159 Hvs Ii) In Madurese Individuals
  5. Rapid Culture Method Using Biphasic Media On Bacteriologic Diagnosis To Detect Mycobacterium Tuberculosis For Determining Pulmonary Tuberculosis
  6. Effect Of Carbide And Cacl2 Concentration On Vitamin C Contents Of Banana Kepok
  7. Direct Cloning Of Melanoma Antigen 1 (mage-1) And The E2 Gene Of Hog Cholera Virus (hcv) From The Blunt End Pcr Product Using Pet 101/d-topo
  8. Quantitation Of Microorganisms In Lower Respiratory Tract Secretions
  9. Bmd-qus Assessment Result Appropriates To Diagnose Osteoporosis
  10. Acid-fast Bacteria M. Leprae Examination In Leprosy Patients Before And After Treatment
  11. Diagnostic Role Of Intra Operative Ovarian Cyst Fluid Cytology In Determining Malignancy
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  13. Basal Insulin As Add-on Therapy To Oral Glucose-lowering Drugs In Insulin Naive Patients With Type 2 Diabetes Mellitus In Primary Public Health Center

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