UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 42 / No. 3 / Published : 2006-07

Order : 6, and page :166 - 171

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Original Article :

Comparison between 0.1% diclofenac natrium and 0.1% dexamethasone eyedrops in reducing cataract postoperative inflammation

Author :

  1. Moestidjab*1
  1. Department of Ophthalmology Airlangga University School of Medicine Dr Soetomo Teaching Hospital, Surabaya

Abstract :

The purpose of this study was to find the difference of effectiveness in suppressing inflammation between the eyedrops 0.1% diclofenac and 0.1% dexamethasone post cataract operation with intraocular lens implantation. This study was an experimental, double blind clinical trial. Patients who met the inclusion criteria were divided randomly into two treatment groups, each receiving 0.1% Na-Diclofenac and 0.1 Dexamethasone eyedrops. The flare and cell count in the anterior chamber was observed in days 1, 2, 7, and 14 post-operative. There were 52 patients who met the inclusion criteria, consisting of 32 males (61.54%) and 20 females (38.46%). The youngest age was 40 years, and the oldest 90 years. It was found that flare and cell count in both treatment groups in days 1, 2, 7, and 14 had no significant difference (p 0.05%), and each group had zero flare and cell count in day 14 post-operatively. Conclusively, 0.1% Na- Diclofenac eyedrop is effective in suppressing inflammation after cataract surgery, so that it can be used as alternative to the steroids.

Keyword :

natrium-diclofenac, dexamethasone, cataract, inflammation, flare,


References :

R Avci,(1993) The effect of diclofenac sodium on postoperative inflammation no info : Eur J Implant Ref Surg

D Elder,(1968) System of Ophthalmology, Disease of Lens London : CV Mosby Co.

WH Havener,(1983) System of Ophthalmology, Disease of Lens St Louis, Toronto : CV Mosby Co.

PA Insel,(1991) Goodman and Gilman's The Pharmacological Basis of Therapeutics New York, Toronto : Pergoman Press

NS Jaffe,(1992) Lens and Cataract New York, London : Gower Medical Publishing

JJ Kanski,(1994) Clinical Ophthalmology Oxford : Butterworth-Heinemann

BG Katzung,(1995) Basic and Clinical Pharmacology Englewood Cliffs New Jersey : Appleton & Lange

MC Kraff,(1994) Efficacy of diclofenac sodium ophthalmic solution versus placebo in reducing inflammation following cataract extraction and posterior chamber lens implantation no info : J Cataract Refract Surg

EC Ku,(1986) Effect of diclofenac sodium on the arachidonic acid cascade no info : Am J Med

P



Archive Article

Cover Media Content

Volume : 42 / No. : 3 / Pub. : 2006-07
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  2. Pattern Of Transforming Growth Factor-ß1 (tgf-ß1) Level In Bph And Non-bph Patients
  3. Changes In The Level Of Acth, Cortisol And Lymphocyte T Count After Establishing Diagnosis Of Hiv And Aids
  4. The Effect Of Aerobic Exercise On The Erythrocyte Osmotic Fragility Of The Wistar White Rats
  5. The Equation Analysis Of Linear Pharmacokinetics Models By Akaike's Information Criterion (aic) Of Diminazene Aceturate In Blood Plasma
  6. Comparison Between 0.1% Diclofenac Natrium And 0.1% Dexamethasone Eyedrops In Reducing Cataract Postoperative Inflammation
  7. The Pharmacokinetics Of Lamivudine In Healthy Rabbit Treated With Cimetidine
  8. Validity And Reliability Of Radar Questionnaire For Patients With Rheumatoid Arthritis
  9. Height Measurement Based On Sternal Bone Length In Adults
  10. Antimicrobial Resistance And Antibiotic Use In Low-income And Developing Countries
  11. Urethral Stricture In Female
  12. Review Article And Clinical Experience: Recent Advances In Diabetes Mellitus: 2002-2005. Selected Clinical Aspects, Clinical Experiences, And Possible Applications

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