UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 50 / No. 4 / Published : 2014-10

Order : 4, and page :222 - 225

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Original Article :

Correlation between preprocedural hscrp level and ck-mb ratio pre and post percutaneous coronary intervention as a marker of preprocedural myocardial injury

Author :

  1. Jaka Fadraersada*1
  2. Siti Sjamsiah*2
  3. Budi Baktijasa*3
  1. Dosen Fakultas Farmasi
  2. Dosen Fakultas Farmasi
  3. Cardiovascular Intervention Diagnostic Unit, Dr. Soetomo Hospital, Surabaya

Abstract :

Patients with type 2 diabetes mellitus may experience inflammation, shown by increased hsCRP levels. Increased hsCRP beforePercutaneus Coronary Intervention (PCI) is sign of PMI, characterized by increased Creatine Kinase-MB. Increased CK-MB afterPCI increases the death risk, myocardial infarction and revascularization. This study was conducted to find correlation betweenpreprocedural hsCRP levels with changes in ratio of CK-MB levels that indicate PMI. This study was an observational analytic studywith cross sectional approach. Patients who fulfilled the inclusion criteria, blood samples were taken before PCI to measure hsCRPlevels and preCK-MB, and 18-24 hours after PCI to measure levels of CK-MBpost. Preprocedural hsCRP levels high if >3mg/L andlow if ≤ 3mg/L. PMI is indication if patient CK-MB ratio ≥ 3 and there is no indication if CK-MB ratio < 3. Analysis of pre and postmeasures CK-MB levels was performed using paired t test. There were 10 patients who fulfilled the inclusion criteria of study. Sixpatients had high levels of preprocedural hsCRP (3.43 to 22.66 mg/L) and 4 patients had low levels of preprocedural hsCRP (0.49 to2.23 mg/L). After PCI action, CK-MB levels increased, with levels of 1.31±0.96 initial CK-MB ng/mL to 3.64 ± 3.50 ng/mL werestatistically significant (p=0.026). Four patients had indication PMI and 6 patients there was no indication. Correlation test resultbetween preprocedural hsCRP levels with indications Periprocedural Myocardial Injury (PMI) showed coefficien =0.250 and did’ntshow statistical significance (p=0.243). We found no correlation between preprocedural hsCRP levels with indications ofPeriprocedural PMI is based on the ratio of CK-MB levels. (FMI 2014;50:222-225)

Keyword :

stable angina, diabetes mellitus type-2, hsCRP, PCI, CK-MB,


References :

Fraker TD, Fihn SD, Gibbons RJ et al,(2007) Chronic Angina focused update of the ACC/AHA 2002 Guidelines for the Management of Patients with Chronic Stable Angina 116, 2762-2772 : Circulation

Lansky AJ, Stone GW,(2010) Periprocedural myocardial infarction: prevalence, prognosis, and prevention 3, 602-610 : Circ Cardiovasc Interv





Archive Article

Cover Media Content

Volume : 50 / No. : 4 / Pub. : 2014-10
  1. Effect Of Touch Therapy On The Growth Of Toddlers (aged 1-3 Years) With Growth Faltering
  2. The Profile Of Genetic Mutation Of The Gyrb Gene On Clinical Isolation Of Acinetobacter Baumannii Resistant To Ciprofloxacin
  3. Relationship Between Platelet Aggregation And Hs-crp In Patients With Pci Receiving Clopidogrel And Aspirin
  4. Correlation Between Preprocedural Hscrp Level And Ck-mb Ratio Pre And Post Percutaneous Coronary Intervention As A Marker Of Preprocedural Myocardial Injury
  5. Evaluation Of Renal Function In Cervix Cancer Patients By Dose Cisplatin 75 Mg/m2 With Nacl-manitol Hydration
  6. Comparison Of Functional Improvement Scale (nihss) Degree Between Acute Intracerebral Hemorrhage Stroke Patients Receiving Standard Treatment And Those Receiving Standard Treatment Plus Celecoxib
  7. Effectiveness Of Kinesio Taping Compared With Short Wave Diathermy On Pain Perception And Functional Status In Knee Osteoarthritis Patients
  8. Cryptosporidium Action In Fecal And Sputum Samples From Patients With Hiv/aids
  9. Percutaneous Transluminal Angioplasty In Patients With Critical Limb Ischemia
  10. Analysis Of Antibiotic Usage In Patients With Bacteremia In The Icu Unit Of Dr. Soetomo Hospital Surabaya
  11. Analysis Of Blood Sample Lysis Rate On Hemoglobin Examination Results Using Rayto Rt. 7600 Auto Hematology Analyzer
  12. Carotid Artery Stenting In A Patient With Transient Ischemic Attack
  13. Risk Factors Of Low Birth Weight (lbw) Incidence. A Case Control Study

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