UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 48 / No. 4 / Published : 2012-10

Order : 3, and page :156 - 162

Related with : Scholar   Yahoo!   Bing

Original Article :

Effect of combined 500 mg vitamin c and 200 iu vitamin e on plasma malondialdehyde level after physical exercise in diving athletes

Author :

  1. Teguh Aryanugraha*1
  2. Harjanto JM*2
  3. Lilik Herawati*3
  1. Mahasiswa Fakultas Kedokteran
  2. Dosen Fakultas Kedokteran
  3. Dosen Fakultas Kedokteran

Abstract :

Every day we are exposed to oxidants. Excessive oxidants may cause various diseases in human body. Oxidants may appear as part of a regular metabolic activity, lifestyle, diet, exogenous exposure, and physical activity. Athletes, including diving athletes, are group that have a risk factor of oxidative stress because of high-intensity physical exercise. Vitamin C and vitamin E are part of the body's defense system against oxidants. However, combination dose of 500 mg of vitamin C and 200 IU of vitamin E in the diving athletes is still not clear. Thirteen diving athletes used as research subjects were divided into two groups. Group A was given a combination of 500 mg of vitamin C and 200 IU of vitamin E for five days and group B was given placebo. On the sixth day, pre-exercise plasma MDA was taken in minute 0, then each athlete was given 100 mg glucose solution + 200 cc water. We started counting minutes since the intake of glucose. Then, the athletes were undergoing physical exercise by diving. In the 30th minute and 60 minutes after glucose intake we took post-prandial plasma MDA. Results of data analysis using paired T test showed significant difference in exercise plasma MDA levels with plasma MDA levels 30' PP in group A and B (p < 0,05). Not-significant differences (p > 0.05) was obtained from the analysis of plasma MDA 30' PP with plasma MDA and MDA plasma 60' PP pre-exercise with plasma MDA 60' PP. Unpaired t test between group A and group B showed no significant difference in plasma MDA levels in any retrieval time (p > 0,05). From these results, it can be concluded that the combination dose of 500 mg vitamin C and 200 IU of vitamin E does not affect plasma MDA levels in athletes, but there is a trend of slightly increase in mean MDA. This could be due to the effects of exogenous antioxidants in reducing free radicals. (FMI 2012;48:156-162)

Keyword :

antioxidants, vitamin C, vitamin E, MDA,


References :

Cooper KH,(1994) Antioxidant Revolution Tennessee : Thomas Nelson

Dahlan MS,(2011) Statistik untuk Kedokteran dan Kesehatan: Deskriptif, Bivariat, dan Multivariat, 5th ed Jakarta : Salemba Medika





Archive Article

Cover Media Content

Volume : 48 / No. : 4 / Pub. : 2012-10
  1. Antibacterial Activity Of Belimbing Wuluh (averrhoa Bilimbi Linn) Extract On Salmonella Typhi Growth
  2. Oral And Topical Aloe Vera Extract Administration In Diabetic Mice (mus Musculus) Wound Healing Process
  3. Effect Of Combined 500 Mg Vitamin C And 200 Iu Vitamin E On Plasma Malondialdehyde Level After Physical Exercise In Diving Athletes
  4. Antibacterial Activity Of Kunyit (curcuma Longa) Leaves Extract On Staphylococcus Aureus Examined Using Dilution Method
  5. Antibacterial Effect Of Strawberry (fragaria X Ananassa) Extract On Pathogenic Serotype 1-11 Escherichia Coli Revealed Using Dilution Method
  6. Guava (psidium Guajava L.) Juice Is Effective In Lowering Blood Glucose Level In Mice (mus Musculus)
  7. Clinical Profile Of Children With Steroid-sensitive Idiopathic Nephrotic Syndrome Relapsing In The First Year At Dr. Soetomo Hospital, Surabaya
  8. The Effects Of Soot Particulate Exposure On Tnf-α Expression In The Mechanism Of Cardiovascular Disorders
  9. Atomoxetine Therapy Effectiveness In Children With Adhd At Day Care, Dr. Soetomo Hospital, Surabaya
  10. Sweet Star Fruit Reduces Blood Pressure In Normotensive Subjects

Information index.php/JIPK/FMI