Folia Medica Indonesiana
ISSN 0303-7932
Vol. 42 / No. 1 / Published : 2006-01
Order : 2, and page :6 - 14
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Original Article :
Effect of laser at pishu point on amount and function of pancreatic β cells (rattus norvegicus) injected by streptozotocin
Author :
- Abdurachman*1
- Department of Anatomy and Histology Airlangga University School of Medicine Surabaya
Abstract :
This study has an objective to obtain experimental laboratory proof on the effect of laser at pishu point (BL-20) in order to increase the number of ß pancreatic cells, enlarge the width of Langerhans’ islets and improve the function of ß cells. The increase of ß cell number and functions was examined using immunohistochemical method to insulin inside the cells. Normal insulin function in the cells was observed from fasting blood glucose. This was a laboratory experimental study using randomized the posttest-only control group design. This study was carried out in Experimental Animal Unit, Department of iochemistry, Airlangga University School of Medicine. A number of 22 rats were divided into two groups. Control group comprised DM rats due to STZ induction, and treatment group comprised STZ-induced DM rats receiving laser at pishu point. Statistical analyses were independent t-test and Spearman's correlation test. It was found that the percentage of pancreatic ß cells and the width of Langerhans’ islets were significantly higher in treatment group (p < 0.05), while fasting blood glucose level was significantly lower in experimental group (p < 0.05). Furthermore, a strong correlation (p < 0.5) was found between the increase of ß cells count, the increased width of Langerhans’ islets and the reduction of fasting blood glucose level. It indicated that the effect of laser at pishu point in STZ-induced DM rats increase the number as well as the function of ß cells.
Keyword :
References :
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Archive Article
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 Volume : 42 / No. : 1 / Pub. : 2006-01 |
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