UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 46 / No. 4 / Published : 2010-10

Order : 9, and page :279 - 281

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Original Article :

Hematocrite as a screening test of iron deficiency occurrence in tetralogy of fallot

Author :

  1. Bagus Setyoboedi*1
  2. Utamayasa A*2
  3. Rahman MA*3
  4. Ontoseno T*4
  1. Department of Child Health, Faculty of Medicine, Airlangga University, Dr. Soetomo Teaching Hospital, Surabaya
  2. Department of Child Health, Faculty of Medicine, Airlangga University, Dr. Soetomo Teaching Hospital, Surabaya
  3. Department of Child Health, Faculty of Medicine, Airlangga University, Dr. Soetomo Teaching Hospital, Surabaya
  4. Department of Child Health, Faculty of Medicine, Airlangga University, Dr. Soetomo Teaching Hospital, Surabaya

Abstract :

Tetralogy of Fallot (TF) is a cyanotic congenital heart disease, characterized by a shunt from right to left and a decrease in blood flow to the lungs. Erythropoiesis as compensation for chronic hypoxia in TF patients often cannot be balanced with adequate reserves of iron, causing iron deficiency and the "relative anemia". Parameters for determining iron deficiency in patients with cyanotic congenital heart disease still in debate. The purpose was to study the use of hematocrite as a screening test incidence of iron deficiency in patients with TF. This was a cross sectional study in patients with Tetralogy of Fallot in Children Cardiac Outpatient Clinic Dr. Soetomo hospital Surabaya during July and August 2004. Samples were taken in consecutive. Result was analyzed with McNemar test and cut-off point was determined with receiver operator characteristic (ROC) curve and contingency C test. Of the 33 patients who were found 14 (42.4%) patients with a hematocrite (HCT) less than or equal to 45% and 19 (57.6%) more than 45%. There was significant positive relationship (r = -0.401, p = 0.021) between the hematocrite with the presence or absence of iron deficiency (transferrine saturation < 11.5%) and MCV < 80 fl). The optimum value of hematocrite in predicting iron deficiency ranged 40% to 45%, with highest sensitivity at 40% hematocrite (94.4%). Conclusion: Hematocrite levels < 40% can be used as screening tests incidence of iron deficiency in patients with TF.

Keyword :

hematocrite, iron deficiency, Tetralogy of Fallot, screening test,


References :

Behrman RE,(2000) Tetralogy of Fallot. In: Behrman RE and Kliegman RM. Nelson Textbook of Pediatrics. 16 th ed Philadelphia : WB Saunders Co.

Hoffbrand AV, Petit JE, Moss PAH,(2001) Essential Haematology, 4th ed Hong Kong : Typesetter Ltd.

Ontoseno T,(2001) Iron deficiency anemia, its prevalence and age distribution pattern of Tetralogy of Fallot patients - : Folia Medica Indonesiana





Archive Article

Cover Media Content

Volume : 46 / No. : 4 / Pub. : 2010-10
  1. Contribution Of Lifestyle And Obesity To The Incidence Of Pre-diabetes
  2. The Importance Of Parenting On Growth And Development In Toddlers
  3. Combination Of Metformin And Hyperbaric Oxygen Therapy Increased Enos Concentration
  4. Description Of Blood Viscosity From Diabetes Mellitus Outpatients In Endocrine Clinic, Aw Sjahranie Hospital, 2009
  5. 2-methoxyethanol Exposure Affects Protein Profile Of Testicular Sperm Membrane In Mice (mus Musculus)
  6. Extract Of Psidium Guajava Leaves Reduces Malondialdehyde In Soleus Muscle Of Wistar Rats Directly After Acute Physical Activity
  7. Occupational Health And Safety Behavior Analysis And Nosocomial Infection Risk In Cleaning Service Workers At Dr. Seotomo Hospital Surabaya
  8. Groundstroke Exercise Combined With Jogging Can Increase The Physical Fitness Of Tennis Players
  9. Hematocrite As A Screening Test Of Iron Deficiency Occurrence In Tetralogy Of Fallot
  10. Comparison Of Maternal Zinc Level In Term Pregnancy Associated With Premature Rupture Of Membranes In Normal Pregnancy
  11. Predominance Of Right Hemisphere In Post-ischemic Stroke Immunity Modulation
  12. Screening In Proteinuria-hematuria Among 5 - 26 Years Old Students In Closed Community School In Surabaya, Indonesia
  13. Non-specific Pattern Of Ultrasonogram (usg) In Lymphoma Of The Breast
  14. Hormonal Status (estrogen Receptors - Progesterone) And Her-2 Neu In Various Cyclin D1 Expressions In Breast Cancer

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