UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 41 / No. 4 / Published : 2005-10

Order : 11, and page :313 - 319

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Original Article :

Immunological aspect on bone cells

Author :

  1. Viskasari Pintoko Kalanjati*1
  1. Department of Anatomy & Histology Airlangga University School of Medicine Surabaya

Abstract :

Immunological aspect on bone cells is closely connected with the existence of estrogen. There are so many immune factors depend on estrogen. Functional interdependence between immune and bone systems is reflected in a number of regulatory molecules acting on the cells of both systems and common precursors for bone and immune cells. Therefore, the disturbances of the immune system may affect bone metabolism, and vice versa. This review addresses the roles of two major immune cell populations, T and B lymphocytes, in the regulation of bone metabolism. Experimental models and human diseases demonstrated that T lymphocytes may produce many bone cell regulatory cytokines, including two essential stimulators of osteoclastogenesis: receptor for activation of nuclear factor kappa b (NF-κB) (RANK) ligand (RANKL) and macrophage colony-stimulating factor (M-CSF). This journal will reveal some of estrogen roles on bone immunology system that can affect bone metabolism.

Keyword :

imune system, bone cells, estrogen,


References :

Cenci S, et al,(2000) Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-α. - : The Journal of Clinical Investigation

Grcevic D et al,(2001) Cellular and molecular interactions between immune system and bone - : CMJ





Archive Article

Cover Media Content

Volume : 41 / No. : 4 / Pub. : 2005-10
  1. Editorial Vol 41 No 4 2005
  2. Opinion: Trend Of Indonesian Nurse’s Role In The Future
  3. Eosinophilia In Physical Exercise Stressor: Pathobiology Or Physiobiology?
  4. The Detection Of Staphylococcus Aureus In Swiftlets' Nest Using Immunohistochemistry (streptavidin Biotin)
  5. The Role Of Intravenous N-acetylcysteine Reduces Pulse Pressure In Patients With Chronic Kidney Disease Stage 5 During Hemodialysis. A Randomized Blinded Trial
  6. Low Fat Milk V/s Low Lactose Milk For Patients With Different Nutritional Status Who Suffered From Acute Diarrhea
  7. Thymidilate Synthase Polymorphisms In Indonesian Childhood Acute Lymphoblastic Leukemia
  8. Modulation Of Immune Response In Long-term Use Of Inhaled Corticosteroid In Childhood Asthma Receiving Specific Immunotherapy
  9. Systemic Lupus Erythematosus Associated With Cholestatic Hepatitis In A Child. A Case Report
  10. Review Article And Clinical Experience: Preventive And Therapeutic Strategies For Osteoporosis (a Highly Efficacious Risedronate-35 Mg Once Weekly)
  11. Immunological Aspect On Bone Cells
  12. Three Dimension Decision For Statistical Testing. The Significance Of Traditional Medicine Holistic Approach (a Preliminary Idea)
  13. Total Quality Management (tqm), The Best Method To Eliminate Narcotics And Psychotropics Abuse And Illegal Distribution

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