Folia Medica Indonesiana
ISSN 0303-7932
Vol. 39 / No. 2 / Published : 2003-04
Order : 4, and page :81 - 85
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Original Article :
Post-adenotonsillectomy monocyte modulation in children with obstructive chronic adenotonsillitis
Author :
- Muhardjo*1
- Department of Otolaryngology Sebelas Maret University School of Medicine Dr Moewardi Hospital, Surakarta
Abstract :
Obstructive chronic adenotonsillitis (OCAT) is an inflammation of adenoid and tonsil that may result in obstruction and followed by hypoxia. As a stressor, hypoxia may modulate immunity. Adenotonsillectomy (ATE) is an indication for surgery for children with OCAT. ATE is a surgical procedure that most commonly undertaken to children. However, the necessity of such operation remains controversial, since adenoid and tonsil are parts of the immune system. The objective of this study was to identify the role of monocyte as a component of post-operative natural immunity. This study used prospective pre-post design. A number of 15 children with obstructive chronic adenotonsillitis (OCAT) underwent operation. Two weeks after operation, a significant reduction of monocyte (p < 0.05) was found. The post-ATE reduction of monocyte count resulted from successful surgical eradication of hypoxia and the source of infection from adenoid and tonsil.
Keyword :
obstructive chronic adenotonsillitis, hypoxia, stressor, adenotonsillectomy,
References :
Adams GL,(1997) Boeis : Buku Ajar Penyakit THT (Boeis Fundamental of Otolaryngology). Translated by Caroline Wijaya. Editor: Harjanto Efendi. Ed-6 Jakarta : EGC
Albert D,(1997) Nasal Obstruction and Rhinorrhoea in Infants and Children. Paediatric Otolaryngology in Scott-Brown's Otolaryngology : Kerr,AG (Edit) 6 th edition Oxford : Butterworth Heinemann
Archive Article
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 Volume : 39 / No. : 2 / Pub. : 2003-04 |
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