Folia Medica Indonesiana
ISSN 0303-7932
Vol. 47 / No. 3 / Published : 2011-07
Order : 6, and page :171 - 173
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Original Article :
Prevalence of hepatitis b, hepatitis c and human immunodeficiency virus infection among pediatric hematology oncology patients with repeated transfusion
Author :
- Mia Ratwita Andarsini*1
- Ari S, Dwi Putri*2
- IDG Ugrasena*3
- Sjamsul Arief*4
- Department of Child Health, Faculty of Medicine, Airlangga University, Dr. Soetomo Hospital Surabaya
- Department of Child Health, Faculty of Medicine, Airlangga University, Dr. Soetomo Hospital Surabaya
- Department of Child Health, Faculty of Medicine, Airlangga University, Dr. Soetomo Hospital Surabaya
- Department of Child Health, Faculty of Medicine, Airlangga University, Dr. Soetomo Hospital Surabaya
Abstract :
Blood transfussion are needed in patients with hereditary hemolitic anemia (particulary Thalasemia), malignancy, hemofilia and aplastic anemia to improve their overall survival. But repeatedly transfusion might carries a risk of blood-borne virus infection such as hepatitis and HIV. This study was conducted to provide prevalence of Hepatitis B, Hepatitis C and HIV infection among patients with repeatedly transfusion. One hundred fifty four patients were enrolled the study, with diagnosis of thalasemia 83 (53.9%) patients, Leukemia 34 (22.1%), Hemophilia 18 (11.7%), aplastic anemia 2 (1.3%) and other malignancy 17 (11%). Prevalence of Hepatitis B, Hepatitis C and HIV infection were 0.6% (1/154), 7.8% (12/154) and 0.6% (1/154) respectively. In this study prevalence of Hepatitis B, Hepatitis C and HIV infection were in agreement with the finding in other study. Education regarding transfusion transmitted infections is of prime importance.
Keyword :
pediatric hematology oncology patients, repeated transfusion, infection,
References :
Bihl F, Castelli D, Marincola F, Dodd RY, Brander C,(2007) Transfusion-transmitted infections - : Journal of Translational Medicine
Borou MG, Zadegan MAA, Zandian KM, Rodan MH,(2009) Prevalence of Hepatitis C Virus (HCV) Among Thalassemia Patients in Khuzestan Province, Southwest Iran - : Park J Med Sci
Jadallah RI, Adwan GM, Abu Hasan MA, Adwan KM,(2005) Prevalence of Hepatitis B Virus Markers Among High Risk Groups in Palestine - : Medical Journal of Islamic World Academy of Sciences
Karimi M, Ghavanini AA,(2001) Seroprevalence of Hepatitis B, Hepatitis C and Human Immunodeficiency Virus Antibodies Among Multitransfused Thalassaemic Children in Shiraz, Iran - : J Paediatr Child Health
Soldan K, Ramsay M, Collins M,(1999) Acute Hepatitis B Infection Associated with Blood Transfusion in England and Wales, 1991-7: Review of Database - : BMJ
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