UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 45 / No. 1 / Published : 2009-01

Order : 13, and page :78 - 87

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Original Article :

Review article and clinical experience: thyroid storm: quick diagnosis and quick treatment. the roles of formulas g/o–p-39.5 – 120 and cs-7.1.5

Author :

  1. Askandar Tjokroprawiro*1
  1. Diabetes and Nutrition Centre, Dr. Soetomo Teaching Hospital, Airlangga University School of Medicine, Jl Mayjen Mustopo 6-8, Surabaya

Abstract :

Thyroid Storm (TS) or Thyroid Crisis (TC) is a sudden, life-threatening thyrotoxicosis or those who are previously unrecognized thyrotoxicosis. The clinical features seen in uncomplicated thyrotoxicosis are generally present and often accentuated in TS, or TS is the most extreme decompensated state of thyrotoxicosis. In the past, TS commonly was observed during thyroid surgery, but today, TS occurs more commonly as a medical rather than a surgical crisis. The clinical picture relates to severely exaggerated effects of thyroid hormones (THs). The clinical picture can be categorized into dysfunctions of 4 cardinal systems: thermo-regulatory system, central nervous system, gastrointestinal-hepatic system,and cardiovascular system. Based on clinical experiences, the author classified TS into classical and non-classical TS. Classical Thyroid Storm can be diagnosed in the presence of goiter (G) and/or orbital (O) signs and precipitant (P) plus body temperature > 39.5°C and heart rate or tachycardia > 120/min. All of these components can be termed as Formula G/O–P-39.5 -120. Non-Classical Thyroid Storm (Table 3) can be diagnosed by using BW-Score. BW-Score has been widely used as a tool of diagnostic criteria for TS. A total score of 45 or greater is highly suggestive of TS. A score of 25-44 is suggestive of impending TS, and a score below 25 is unlikely to represent TS. On the basis of clinical experiences, Formula TS – 41668.24.6 has been used as of the year 2005 as specific practical guideline in the treatment of TS and as the therapeutic clinical outcomes.

Keyword :

thyroid storm, thyroid crisis, thyrotoxicosis, classical thyroid strom, non-classical thyroid storm, Formula G/O–P-39.5 -120, BW-score, Formula TS – 41668.24.6,


References :

Burch HB, Wartofsky L,(1993) Life-threatening thyrotoxicosis: Thyroid Storm - : Endocrinol Metab Clin North Amer

Ghobrial MW, Ruby EB,(2002) Come and Thyroid Storm in Apathetic Thyrotoxicosis - : South Med J





Archive Article

Cover Media Content

Volume : 45 / No. : 1 / Pub. : 2009-01
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  2. The Effectiveness Of Acid Phosphatase And Zinc Tests On The Seminal Fluid Spot Examination As The Primary Identification. A Laboratory Observational Study
  3. The Relationship Between The Width And That Of Dental Arch Of The Upper Jaw In Patients With Down’s Syndrome Which Is Measured By Anthropometric Methods
  4. Immuno-modulatory Effect Of Probiotic And Sublingual Immunotherapy In Asthmatic Children
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  6. Isolation Of Male Antifertility Compound In N-butanol Fraction Of Justicia Gendarussa Burm. F. Leaves
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  8. Hyaluronan, Tnf-α And Estradiol Concentrations In Infertile Women With Endometriosis
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  10. Antiseizure And Neurotoxicity Effects Of Ligustrosid Glycoside Isolated From Fraxinus Graffithii Clarke Compared To Phenytoin And Diazepam
  11. Effect Of Andrographis Paniculata Extract On Mammary Carcinoma In Rats Induced By Dmba
  12. Review Article: Ultrasound Elastography: Development Of The Imaging Technique For Tissue Elasticity Assessment
  13. Review Article And Clinical Experience: Thyroid Storm: Quick Diagnosis And Quick Treatment. The Roles Of Formulas G/o–p-39.5 – 120 And Cs-7.1.5

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