Folia Medica Indonesiana
ISSN 0303-7932
Vol. 49 / No. 3 / Published : 2013-07
Order : 3, and page :146 - 149
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Original Article :
Sero-epidemiological study on dengue virus infection in four indonesian cities
Author :
- Soegeng Soegijanto*1
- Kris Cahyo Mulyanto*2
- Siti Churotin*3
- Tomohiro Kotaki*4
- Masa Nori Kamioka*5
- Eiji Konichi*6
- Atsusi Yamanaka*7
- Dyah Wikanesthi*8
- Institut of Tropical of Disease Airlangga University, Surabaya, Indonesia
- Institut of Tropical of Disease Airlangga University, Surabaya, Indonesia
- Institut of Tropical of Disease Airlangga University, Surabaya, Indonesia
- Center for Infectious Disease, Kobe University Graduate School of Medicine, Japan
- Center for Infectious Disease, Kobe University Graduate School of Medicine, Japan
- Center for Infectious Disease, Kobe University Graduate School of Medicine, Japan
- Center for Infectious Disease, Kobe University Graduate School of Medicine, Japan
- Soerya Hospital, Sidoarjo, Indonesia
Abstract :
Dengue virus (DENV) infection is recognized as a major public health problem; >50 million persons are infected each yearworldwide. Molecular epidemiology studies have investigated the possibility of a link between particular DENV genotype or clusteror particular clinical form of disease. Consequently, finding new viral genotypes in areas where they had been absent could be ofepidemiologic and clinical interest. The aim of this study is to identify the serotype of dengue virus in Surabaya, Sidoarjo, Bangkalanand Mataram. Human sera were obtained from 392 patients presenting clinical manifestations of dengue and tested for anti-dengueIgM antibodies (Becton-Dickinson). Dengue-infected samples were obtained during the first five days of the onset of fever and wereprocessed for anti dengue IgM detection using IgM capture ELISA (MAC-ELISA). In Surabaya, 182 of 203 sample (2011) and 79 of86 sample (2012) were D1 serotype. In Sidoarjo, 40 of 43 sample (2011) and all of 17 sample (2012) were D1 serotype. InBangkalan, 23 of 24 sample (2013) and in Mataram all of 4 sample were D4 serotype. We can conclude that in Surabaya andSidoarjo the most Dengue Virus serotype is D1, while in Bangkalan and Mataram the most Dengue Virus serotype is D4.(FMI2013;49:146-149)
Keyword :
Dengue Virus, Serotype, Sero-epidemiological,
References :
Guzmán MG, Kouri GP, Bravo J, Soler M, Vazquez S, Morier L,(1990) Dengue haemorrhagic fever in Cuba, 1981: a retrospective epidemiological study - : Am J Trop Med Hyg
Guzmán MG and Kouri G,(2002) Dengue: an update - : Lancet Infect Disease
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