UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 41 / No. 2 / Published : 2005-04

Order : 6, and page :102 - 107

Related with : Scholar   Yahoo!   Bing

Original Article :

The comparison of the effectiveness between 2.5% povidone-iodine eye drop and 1% tetracycline eye ointment on bacterial ophthalmia neonatorum prophylaxis

Author :

  1. Hamidah Ali and Retno Sutarti*1
  1. Department of Ophthalmology Airlangga University School of Medicine Dr Soetomo Teaching Hospital, Surabaya

Abstract :

Background: Ophthalmia neonatorum is an acute conjunctivitis in infant caused by bacterial gram positive, gram negative, herpes virus and HIV virus. The most frequent bacterial causes are perinatally-acquired gonococcus and chlamydia. Before prevention the cases demonstrated a high rate and after prevention the rate is decreased. Many preventive agents are used including 1% silver nitrate solution, 0.5% erythromycine eye ointment and 2.5% povidoneiodine eye drop (new application). Every country chooses and recommends those drugs differently as prophylaxis. Objective: To know the difference of the effectiveness between 2.5% povidone-iodine eye drop and 1% tetracycline eye ointment in newborn at Dr. Soetomo Hospital. Method: This study used experimental pre- and posttest design, i.e. comparing the effectiveness between 2.5% povidone-iodine eye drop and 1% tetracycline eye ointment. Population of study were 148 normal babies, divided into two groups: i.e., group one of 74 babies treated with 2.5% povidone-iodine eye drop and the second group comprised 74 babies with 1% tetracycline eye ointment. The data were collected and analyzed statistically with Chi-square test, Wilcoxon sign rank tests, Mann Whitney, McNemar and homogeneity test (p < 0.05 significantly). Result: the effectiveness of 2.5% povidone-iodine eye drop and 1% tetracycline eye ointment, both clinically and laboratory, were good. The differences were not significant. Chi - square test in clinical examinations showed that conjuctival hyperaemie had p= 1.000, conjunctival secretion had p= 0.202, Laboratory examinations revealed: polymorphonuclear cell p = 0.831, mononuclear cell p = 0.154 and the decrease of bacteria = 0.147. Conclusion: The effectiveness of 2.5% povidone-iodine eye drop and 1% tetracycline eye ointment is similar p > 0.05, thus 2.5% povidone-iodine can be considered as prophylaxis in newborn babies.

Keyword :

ophthalmia neonatorum, povidone-iodine, tetracycline,


References :

Friendly SD,(1983) Ophthalmia Neonatorum: Pediatric Clinics Of North America, Vol. 30 Washington DC : George Washington University

Havener WH,(1983) Ocular Pharmacology: Tetracycline St. Louis, Toronto : CV Mosby Company





Archive Article

Cover Media Content

Volume : 41 / No. : 2 / Pub. : 2005-04
  1. Editorial Vol 41 No 2 2005
  2. Opinion: Bioethics. Its Role In Research
  3. Gastroprotective Effect Of Curcumine On Ethanol-induced Gastric Mucosal Lesions In Rats
  4. Spermatozoa Motility And Morphological Recovery Process In Mice (mus Musculus) After The Induction Of 2-methoxyethanol
  5. Nutritional And Immune Effects Of Early Enteral Feeding Supplemented By Arginine, Glutamine And Omega 3 Fatty Acid In Critically Ill Patients
  6. The Comparison Of The Effectiveness Between 2.5% Povidone-iodine Eye Drop And 1% Tetracycline Eye Ointment On Bacterial Ophthalmia Neonatorum Prophylaxis
  7. The Effectiveness Test Of Eyedrop Lodoxamide Tromethamine 0.1 % And Sodium Cromoglycate 2% In Vernal Keratoconjunctivity In Dr. Soetomo Hospital, Surabaya
  8. Risk Factors Of Symptomatic And Asymptomatic Osteoarthritis Of The Knee
  9. Brain Natriuretic Peptide As An Indicator Of Left Ventricle Dysfunction And A Predictor Of Cardiovascular Events In Acute Coronary Syndromes
  10. Management Of Perioperative Pulmonary Edema In Patient With Pre-eclampsia/eclampsia Undergoing C-section
  11. Water Source As The Risk Factor Of H. Pylori Infection In Chidren Aged 0 - 5 Years In Suburban Area Of Surakarta
  12. Clinical–epidemiological Data On Hiv/aids Patients Admitted To A Top Referral Hospital During 1997-2005. A Database For Action In The Future, Referring To Another Developing Countries
  13. Review Article And Clinical Experience: New Insights Into Oral Agents In The Treatment Of T2dm (the Roles Of Fixed-dose Oral Agents Combination)
  14. Literature Review: Choosing A Prosthetic Heart Valve

Information index.php/JIPK/FMI