Folia Medica Indonesiana
ISSN 0303-7932
Vol. 42 / No. 4 / Published : 2006-10
Order : 3, and page :213 - 217
Related with : Scholar Yahoo! Bing
Original Article :
The role of care, support and treatment to biological parameters and clinical changes of plwha in idicu
Author :
- Nasronudin*1
- Tropical and Infectious Diseases Division, Department of Internal Medicine Airlangga University School of Medicine Dr Soetomo Teaching Hospital, Surabaya
Abstract :
There have been many recent excellent reviews of the role of care, support and treatment (CST) factors in the onset and course of disease like HIV&AIDS infection. As knowledge of the underlying immunological mechanisms in HIV & AIDS is developed, more attention was directed at possible links between the immune system and psychosocial and biological influences, as well as the immune and central nervous system. This study was aimed to disclose the CST influences to biological parameters (CD4, total T lymphocytes) and clinical changes of HIV&AIDS patients. This study used observational design with panel study approach in IDICU. Fourteen HIV&AIDS infection patients taken by simple random sampling were enrolled in this research. Fourteen persons with a high risk of HIV infection non-reactive served as control. Three times examinations were done in this research. The first, when the patients had not known the HIV infection status in the first day of signing the informed consent, the second (day-7) they were are in acute stress condition after HIV infection diagnosis is informed, and the third (day-31), they were in chronic stress condition and acceptance of this disease. The result of this research was subjected to multivariate analysis. The result of the first examination reveal that CD4 declined both of the HIV infection and non HIV infection group, less than 1000 cells/mm3. The decline progressed faster in the HIV group. Second examination showed CD4 declined not only by stimulation of biological stress HIV to lymphocytes but also to other immune cells. The decline also progressed faster in HIV group The result of the third examination revealed that CD4 decline progressed faster in the HIV than non-HIV group. It wasfound that lymphocyte count of both the HIV infection and non-HIV infection groups had no significant difference. Care, support and treatment can reduce stigma and other negative consequences of being HIV-positive and in this way make people less reluctant to seek HIV counseling and testing. In conclusion, CD4, total T lymphocytes and clinical performance are very unique on HIV/AIDS patients. CD4 decline is not always followed by the decline performance status. Associations of PLWH, peer group, family members, doctors, nurse, community support are a good example of community mechanisms that provide both of psychological and psychosocial support.
Keyword :
CST influence, biological and clinical parameters, PLWHA,
References :
D Atanackovic,(2002) Acute psychological stress simultaneously alters hormone levels, recruitment of lymphocyte subsets, and production of reactive oxygen species no info : Immunol Invest
MC Brunner-Weinzierl,(2002) Acute psychological stress simultaneously alters hormone levels, recruitment of lymphocyte subsets, and production of reactive oxygen species no info : Immunol Invest
H Kroger,(2002) Acute psychological stress simultaneously alters hormone levels, recruitment of lymphocyte subsets, and production of reactive oxygen species no info : Immunol Invest
S Serke,(2002) Acute psychological stress simultaneously alters hormone levels, recruitment of lymphocyte subsets, and production of reactive oxygen species no info : Immunol Invest
HC Deter,(2002) Acute psychological stress simultaneously alters hormone levels, recruitment of lymphocyte subsets, and production of reactive oxygen species no info : Immunol Invest
MW Becher,(2004) Infectious Diseases
Archive Article
| Cover Media | Content |
|---|---|
 Volume : 42 / No. : 4 / Pub. : 2006-10 |
|
