UNIVERSITAS AIRLANGGA



Detail Article

Indonesian Journal of Medical Microbiology

ISSN

Vol. 1 / No. 1 / Published : 2012-12

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Original Article :

Susceptibility pattern of mycobacterium tuberculosis from bronchoalveolar lavage (bal) specimen

Author :

  1. Deby Kusumaningrum*1
  2. Rebekah J. Setiabudi*2
  3. Ni Made Mertaniasih*3
  1. Department of Microbiology, Faculty of Medicine, Airlangga University
  2. Department of Microbiology, Faculty of Medicine, Airlangga University, Surabaya
  3. Department of Microbiology, Faculty of Medicine, Airlangga University, Surabaya

Abstract :

A high quality specimen is essential for accurate laboratory diagnosis of tuberculosis infection, especially in severe or complicated case of pulmonary tuberculosis infection. Specimen from bronchoalveolar lavage (BAL), which is taken directly from the source of tuberculosis infection sites in the lung, has better quality than spontaneous sputum. BAL specimen is expected to have high sensitivity for diagnosing tuberculosis infection in negative smears cases or difficult pulmonary tuberculosis infection. The aim of this research is to study the susceptibility pattern of Mycobacterium tuberculosis complex (MTBC) from BAL specimen. BAL specimens were collected from Clinical  Microbiology Laboratory of  Dr. Soetomo Hospital throughout April-July 2012. The susceptibility to first line Anti tuberculosis drug  of each specimen was  examined  using liquid method of MGIT 960 system. From 95 BAL specimens, the positive  cultures of all BAL specimens  showed that  39 were Mycobacterium tuberculosis complex positive; 9 isolates  were sensitive to  Streptomycin, 8 isolates sensitive to Isoniazide,  38 isolates were sensitive to Rifampicine, and  23 isolates were sensitive to Ethambutol. In conclusion, BALspecimen  detection is very useful in acquiring accurate results for diagnosing of pulmonary tuberculosis infection.

Keyword :

BAL specimen, Mycobacterium tuberculosis complex (MTBC), Pulmonary TB ,


References :

Mosby,(2009) Medical dictionary, 8th edition London : Elsevier





Archive Article

Cover Media Content

Volume : 1 / No. : 1 / Pub. : 2012-12
  1. Antimicrobial Activity Of Hibiscus Sabdariffa Calyx Extract Against Shigella Dysenteriae In Vitro
  2. Bactericidal Effect Of Cempedak (artocarpus Champeden) Stem Extract On Mycobacterium Tuberculosis
  3. Antibacterial Activity Of Papaya Leaves (carica Papaya,l) Infusum Against Escherichia Coli
  4. Ziehl Neelsen Stain Sensitivity In Determining The Etiologic Of Granulomatous Inflammation
  5. Comparative Antibacterial Activity Of Noni Fruit Versus Ciprofloxacin Against Salmonalla Typhii In Vitro
  6. Susceptibility Pattern Of Mycobacterium Tuberculosis From Bronchoalveolar Lavage (bal) Specimen

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