Journal of Basic Medical Veterinary
ISSN 2302-6820
Vol. 4 / No. 2 / Published : 2015-12
Order : 6, and page :113 - 118
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Original Article :
Effects of plant wood yellow leaf extract (arcangelisia flava merr) as to prevent hepatic dysfunction examination levels of bilirubin, sgot sgpt and serum blood on white rat (rattus norvegicus)
Author :
- Rentain Ginal*1
- M.Gandul Atik Yuliani*2
- Hani Plumeriastuti*3
- Mahasiswa Fakultas Kedokteran Hewan
- Dosen Fakultas Kedokteran Hewan
- Dosen Fakultas Kedokteran Hewan
Abstract :
The reseach objective is to prove that the administration of yellow wood leaf extract (Arcangelisia flava merr) may prevent hepatic dysfungction by inspection of SGPT (Serum Glutamic Piruvic Transaminase) and SGOT (Serum Glutamic Oksaloasetic Transaminase) level in the blood serum of rats (Rattus norvegicus). Twenty five rats devided in 5 groups (P0-, P0+, P1, P2, P3) yellow wood plant leaf extract was given to each group P1, P2, P3 with the dose of 5mg, 10 mg and 20 mg for 5 day. CMC Na was given to P0- for 10 days. Acetaminofen was given to P0+, P1, P2, P3 since day 6-10. The result of this study showed that there was the significan decreasing of sgpt in 5 mg of dose.
Keyword :
yellow wood, Arcangelisia flava merr, SGOT-SGPT, bilirubin, rats blood serum,
References :
Dufour, D.R. ., J.A. Lott and F.S. Nolte. . ,(2000) Diagnosis and Monitoring Hepatic Injury. I. Performance Characteristics of Laboratory Test. 46 : 2050-2068. : Clinical Chemistry.
Rantala, M. and J.W. Van de Laar. . ,(2008) Survaillance and Epidemiology of Hepatitis B and C in europe. 13(21) :13-23. : A Review. Eurosurvaillance.
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