Journal of Basic Medical Veterinary
ISSN 2302-6820
Vol. 6 / No. 2 / Published : 2017-12
Order : 12, and page :161 - 167
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Original Article :
Potential protection of tomato paste (lycopersicon esculantum) against kidney histopathologic picture of mice (mus musculus) exposed to borax
Author :
- Titis Jesica Aviv*1
- Djoko Legowo *2
- Eduardus Bimo Aksono *3
- Mahasiswa Fakultas Kedokteran Hewan
- Dosen Fakultas Kedokteran Hewan
- Dosen Fakultas Kedokteran Hewan
Abstract :
This research was aimed to evaluate the potential protection of tomato paste (Lycopersicon esculatum) against kidney histopathologic picture of mice (Mus musculus) exposed to borax. Twenty-four male mice (Mus musculus) 60-90 days old with average weight of 20 g is used. These animals were divided into six groups (P0, P1, P2, P3, P4, and P5). P0 treated with sterile aquadest of 0.1 ml / 20g Bw / day, P1 is treated with borax 7.5 mg / 20g Bw / day, P2 is treated with tomato paste 0,3 g / 20g Bw / day, P3 is treated with tomato paste 0, 15 g / 20g Bw / day and borax 7.5 mg / 20g Bw / day, P4 is treated with tomato paste 0,3 g / 20g Bw / day and borax 7.5 mg / 20g Bw / day, and P5 treated with tomato paste 0.45 g / 20g Bw / day and borax 7.5 mg / 20g Bw / day. This research has been conducted for 14 days. Data were compared using non-parametric test of Kruskal-Wallis and showed that among the treatment group contained significant effect (p <0.05), then continued with Man-Whitney test using SPSS 20.0 for windows. The results showed that the tomato paste 0.45 g / BB 20g daily can reduce the degree of kidney damage in mice exposed to borax significantly (p <0.01).
Keyword :
tomato , paste, borax, kidney,
References :
Akbar, B,(2010) Tumbuhan Dengan Kandungan Senyawa Aktif Yang Berpotensi Sebagai Bahan Antiferilitas - : Adabia Press, Jakarta
Diener, R. M. and M. S. Christian,(2008) Lycopene Overview: What It Is and What It Does, Lycopene Nutritional, Medicinal and Therapeutic Properties Page 4-10 : Science Publisher. London United Kingdom
Baiano, A., P. Tamagnone, V.Marchitelli, dan M. A. D. Nobile,(2005) Quality decay kinetics of semi-preserved sauce as affected by packaging Vol 70. No. 2: 92-97 : Journal of Food Science
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