UNIVERSITAS AIRLANGGA



Detail Article

Journal of Basic Medical Veterinary

ISSN 2302-6820

Vol. 6 / No. 2 / Published : 2017-12

Order : 9, and page :142 - 147

Related with : Scholar   Yahoo!   Bing

Original Article :

The effect of spirulina platensis extract on histopatology of white male rats (rattus norvegicus) in oxidative stress

Author :

  1. Yohana Yekti Piwi*1
  2. Nove Hidajati *2
  3. Sri Mulyati *3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

The objective of this research is to identify the effect of Spirulina platensis extract to histopatology description  of white male rats (Rattus norvegicus) in oxidative stress with swimming in 1 hour for 35 days. This research uses 20 two-month-old white male rats with 150 – 200 gram in average. Those rats are divided into 5 groups: (1) negative control group which is given 1 % Na-CMC, (2) positive control group which is treated swimming for an hour in 28 days, (3) first treatment (P1) group which is given 300 mg/kg BW Spirulina platensis then they swim for an hour, (4) second treatment group (P2) which is given 600 mg/kg BW Spirulina platensis then they swim for an hour, (5) third treatment group (P3) which is given 1200 mg/kg BW Spirulina platensis then they swim for an hour. In the end of the experiment, all rats are euthanized and their livers are taken for scoring. This research result shows that Spirulina platensis extract can improve white male rats liver histopatology in oxidative stress. These result show that Spirulina platensis extract could provide a significant protection from stress oksidative with 300 mg/ kg body weight, per oral.

Keyword :

Spirulina platensis, Rattus norvegicus, oxidative, stress,


References :

Towatana, NH, Reamongkol, W, Wattanapiromsakul,C, and Bunkrongcheap, R,(2010) Acute and toxicity evaluation of the hydroethanolic extrac of mangosteen pericarp Vol.4(10), pp 956-974 : Journal of medical Plants Research

Oliveira, M.A.C.L. De, M.P.C. Monteiro, P.G. Robbs, and S.G.F. Leite.,(2010) Growth and Chemical Composition of Spirulina platensis biomas at different temperatures 7:261-275 : Aquaculture International





Archive Article

Cover Media Content

Volume : 6 / No. : 2 / Pub. : 2017-12
  1. Critical Percentages By Adding Alcohol 70% Toward Water In Oil Cream
  2. Protective Effect Of Propolis Extract On Histopathological Features Of Mice’s (mus Musculus) Liver Induced By Lead Acetate
  3. Most Probable Number Of Escherichia Coli On Beef Of Cattle At Krian Sidoarjo Abattoir
  4. The Effect Of Ginger Juice (zingiber Officinale) On Milkfish (chanos Chanos) Total Bakterial
  5. Analysis Of Helminthiasis On Sumatran Tiger (panthera Tigris Sumatrae) In Gunung Bayan Lestari Zoo At West Kutai District East Borneo
  6. The Influence Of Tomato Paste (lycopersicon Esculentum) Administration Against To The Number Of Leydig Cells Of Mice (mus Musculus) Exposed To Borax
  7. Hepatoprotective Potency Of Tomato Pasta (lycopersicon Esculentum) Against Histopathological Appereance Of Mice (mus Musculus) Liver Exposed To Borax
  8. Effect Different Concentration Of Ethanol Extract Tree Marigold (tithonia Diversifolia (hemls.) A. Gray) Leaves Against Candida Albicans
  9. The Effect Of Spirulina Platensis Extract On Histopatology Of White Male Rats (rattus Norvegicus) In Oxidative Stress
  10. Rat’s Algor Mortis In Room With Ambient Temperature And Room With 20°c Temperature
  11. Pengaruh Pemberian Ekstrak Bawang Bombay (allium Cepa L.) Terhadap Tikus Putih Penderita Diabetes Mellitus
  12. Potential Protection Of Tomato Paste (lycopersicon Esculantum) Against Kidney Histopathologic Picture Of Mice (mus Musculus) Exposed To Borax

Information index.php/JIPK/JBMV