UNIVERSITAS AIRLANGGA



Detail Article

Jurnal Farmasi dan Ilmu Kefarmasian

ISSN

Vol. 2 / No. 1 / Published : 2015-10

Order : 1, and page :1 - 4

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Original Article :

Formulasi losio antinyamuk dengan zat aktif minyak atsiri lantana camara linn

Author :

  1. Syaiful Katadi*1
  2. Ahmad Zaeni*2
  3. Suryani*3
  4. Rini Hamsidi*4
  1. Jurusan Farmasi, Fakultas Farmasi, Universitas Halu Oleo
  2. Jurusan Farmasi, Fakultas Farmasi, Universitas Halu Oleo
  3. Jurusan Farmasi, Fakultas Farmasi, Universitas Halu Oleo
  4. Jurusan Farmasi, Fakultas Farmasi, Universitas Halu Oleo

Abstract :

This study aims to formulate antimosquito lotion preparations that use active substances volatile oil from the leaves of Lantana camara Linn. Essential oils obtained by steam distillation of leaves of L. camara. The process of making lotion by mixing volatile oil into lotion base with a concentration of 1%, 2%, 3%, 4%, 5% at a temperature of 50-30oC. The analysis which performed on lotion is stability test that includes organoleptic, pH, viscosity and globule size with observations for 60 days of storage. Test lotion mosquito activity is done by calculating the time of protection, that is the time when the hand is inserted into the breeder panelists until mosquito bite. From the results of stability tests, the organoleptic lotion does not show changes in color and smell, as well as showing good homogeneity. There was a decrease of pH lotion for 60 days of storage and there is a real difference (<α 0.05) between pH lotion on the first day until day 60. Lotion pH range between 5 to 6. However the pH still in the range of required pH which is from 4,0 to 7.5. Lotion viscosity is in the range 2166-4500 cP. Statistic results showing significant differences that occurred in the viscosity during storage lotion, but the viscosity still qualified which is less than 30,000 cP. Globule size ranged from 0.07 to 0.3 mm (100x magnification). Globule size had enlarged for 60 days of storage but not much different when compared with the comparative preparations. Based on the results of the stability test, the resulting lotion has good stability and still meet safety standards and to be applied to the skin. the result of mosquito activity showed lotion with a concentration of 5% is give largest activity. The larger activity according with the amount of volatile oil of L. camara were added to the lotion. This shows that volatile oil of L. camara has activity as a anti-mosquito.

Keyword :

Lotions, L.camara, anti-mosquito, formulations, essential oils,


References :

Ameliana L, Lina W,(2011) Uji Aktivitas Antinyamuk Losio Minyak Kunyit sebagai Alternatif Pencegah Penyebaran Demam Berdarah Dengue 1 (2), 138-139 : J. Trop. Phar. Chem

Ditjen POM,(1995) Farmakope Indonesia Edisi IV. Hal. 450-451, 1124, 1144, 1165, 1210 : Departemen Kesehatan R.I

Gandahusada S, Herry DI, Pribadi W,(1998) Parasitologi Kedokteran Edisi ke-3 : Balai Penerbit FKUI, Jakarta

Gozali D, Ida M, Mutakin, Kartika,(2009) Uji aktivitas antinyamuk dari ekstrak daun zodia (Evodia suaveolens scheff.) Terhadap nyamuk Culex fatigans dalam sediaan 7 (3), 28-31 : Farmaka

Panghiyangani R, Rahmiati NAF,(2009) Potensi Ekstrak Daun Dewa (Gynura pseudochina Ldc) Sebagai Larvasida Nyamuk Aedes aegypti Vektor Penyakit Demam Berdarah Dengue 1(2), 121-122 : Jurnal Kedokteran Indonesia





Archive Article

Cover Media Content

Volume : 2 / No. : 1 / Pub. : 2015-06
  1. Formulasi Losio Antinyamuk Dengan Zat Aktif Minyak Atsiri Lantana Camara Linn
  2. Development Potentiometric Sensor-coated Wire Cyanide Ion Selective Electrode Based Aliquat336 Membranes For Determination Cyanide In Gadung (dioscorea Hispida Dennus)
  3. Studi In Silico Gendarusin A, B, C, D Dan E Untuk Prediksi Aktivitas Terhadap Enzim Cyp17a1 Sebagai Afrodisiaka
  4. Isolasi Senyawa Terpenoid Dari Fraksi N-heksana Daun Marsilea Crenata Presl. Pada Hasil Kcv Fraksi No.2
  5. Pengaruh Pasta Tomat (solanum Lycopersicum L.). Pada Pertumbuhan Dan Daya Hambat Lactobacillus Acidophilus Fncc-0051 Dan Lactobacillus Plantarum Fncc-0027 Terhadap Candida Albicans
  6. Aktivitas Antibakteri Susu Probiotik Lactobacilli Terhadap Bakteri Penyebab Diare (escherichia Coli, Salmonella Typhimurium, Vibrio Cholerae)
  7. Aktivitas Penghambat Asetilkolinesterase Ekstrak Etanol 96 Persen Daun Syzygium Cumini, Syzygium Aromaticum, Syzygium Polyanthum Dan Syzygium Aquaeum

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