Jurnal Oftalmologi Indonesia
ISSN 1693-2587
Vol. 7 / No. 3 / Published : 2010-06
Order : 4, and page :103 - 105
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Original Article :
Human papilloma virus in progressive pterygium and stationary pterygium
Author :
- Bragastio Sidharta*1
- Suhardjo*2
- Hartono*3
- Department of Ophthalmology, Faculty of Medicine Airlangga University/Dr. Soetomo General Hospital, Surabaya
Abstract :
The purpose of this study is to compare the proportion of HPV between progressive and stationary pterygium. This study used across-sectional research design. The subject of this study was patients with primary pterygium presenting to the teaching hospital ofFaculty of Medicine Gadjah Mada University in Yogyakarta and its networking hospitals. Examination was performed to 62 pterygiumtissues, 31 of which were progressive pterygia and 31 were of stationary pterygia. All pterygium tissues were examined by a PolymeraseChain Reaction (PCR) technique with a primer DNA of a single strand HPV Hela. An HPV-positive was present in 66.7% of cases ofprogressive pterygium and only 22.6% of cases of stationary pterygium with p < 0.05 (p = 0.001). The result of this study showed thatthe proportion of HPV-positive in progressive pterygium was greater than stationary pterygium
Keyword :
progressive pterygium, stationary pterygium, human papillomavirus, polymerase chain reaction,
References :
Duke Elder S,(1987) Disease of the Outer Eye. System of Ophthalmology London : Henry Kimpton
Gerundo M,(1988) On the Etiology and Pathology of Pterygium - : Am. J. Ophthal
Dushku N, John M, Schultz GS, Reid TW,(2002) Pterygia pathogenesis: corneal invasion by matrix metalloproteinase expressing altered limbal epithelial basal cells - : Arch Ophthalmol
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