Jurnal Oftalmologi Indonesia
ISSN 1693-2587
Vol. 7 / No. 4 / Published : 2010-12
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Original Article :
The profile of tear mucin layer and impression cytology in pterygium patients
Author :
- Djajakusli Shintya*1
- Rukiah Syawal*2
- Junaedi Sirajuddin*3
- Noor Syamsu*4
- Department of Ophthalmology, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo General Hospital, Makassar
- Department of Ophthalmology, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo General Hospital, Makassar
- Department of Ophthalmology, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo General Hospital, Makassar
- Department of Ophthalmology, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo General Hospital, Makassar
Abstract :
The purpose of this study is to assess the profile of tear mucin layer and impression cytology in eyes with and without pterygium. A cross sectional study was conducted in Dr. Wahidin Sudirohusodo Hospital and BKMM Makassar. Patients with unilateral primary pterygium who visited both centers during the period from 1 January to 31 August 2009 were included. There were 34 subjects (68eyes) with unilateral primary pterygium fulfilled the criteria. Tear mucin layers were examined by Break Up Time (BUT) test, Tear Ferning Test (TFT) and impression cytology test of the bulbar conjunctiva on both eyes of the subjects with pterygium as well as fellow eye (without pterygium). The result of this study showed that average BUT value in eyes with pterygium was 8.44 seconds and in eyes without pterygium was 13.84 seconds. TFT degree in eyes with pterygium was grade 3 and 4 while eyes without pterygium was grade1 and 2. Impression cytology in eyes with pterygium was grade 2–3, while eyes without pterygium was grade 0–1. These differences were statistically significant (p <0.05). No significant correlation was found between patient’s condition (age, sex and occupation) and tear mucin layer, impression cytology. Most of cases with medial pterygium, third stage and intermediate (T2)/fleshy (T3) pterygium type had abnormalities in mucin and impression cytology. It is concluded that there are significant abnormalities of tear mucinlayer and impression cytology in eyes with pterygium
Keyword :
tear mucin layer, BUT, TFT, impression cytology, unilateral primary pterygium,
References :
Gazzard G, et al,(2002) Pterygium in Indonesia: prevalence, severity and risk factors Inggris : Br J Ophthalmol
Skolnick CA, Grimmet MR,(2005) Management of pterygium In: Krachmer JH, Mannis MJ, Holland EJ Philadelphia : Philadelphia: Elsevier Mosby
McCarty CA, Fu CL, Taylor HR,(2000) Epidemiology of pterygium in Victoria Australia : Br J Ophthalmol
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