UNIVERSITAS AIRLANGGA



Detail Article

Jurnal Oftalmologi Indonesia

ISSN 1693-2587

Vol. 7 / No. 5 / Published : 2011-06

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Original Article :

The risk factors of human papilloma virus 18 on the recurrences of pterygium

Author :

  1. Josefien SM Saerang*1
  1. Department of Ophthalmology, Faculty of Medicine Sam Ratulangi University/Prof. Dr. R.D. Kandou General Hospital, Manado

Abstract :

This study which was done in nested case control study in prospective cohort design is aimed to analyze the risk factors of Human Papilloma Virus in the recurrence of pterygium. The samples were pterygium patients came at BLU RSUP Prof. R. D. Kandou Manado,Airmadidi Hospital, and Belang district primary health care provider who seek for medical help. The study was started on January 2010 until December 2010 with total samples were 99 patients and 104 eyes. 104 eyes was operated using Conjunctival Limbal Autograft(CLAG) technique with fibrin glue. PCR assessment of 104 eyes was 88 eyes positive with Human Papilloma Virus type 18 (HPV-18).52 patients (56 eyes) came to follow up; of which 48 eyes were recurrence with 47 eyes positive with HPV-18. HPV 18 has a strong role in the recurrence of pterygium (p < 0.05).

Keyword :

pterygium, recurrence, HPV 18,


References :

Rodrigues FW, Arruda JT, Silva RE,(2008) TP53 gene espression, codon 72 polymorphism and human papillomavirus DNA associated with pterygium - : Genetics and molecular research

Perra MT, Maxia C, Cobu A,(2006) Oxidative stress in pterygium: relationship between p53 and 8-hydroxydeoxyguanosine - : Molecular vision

Saw SM, Banerjee K, Tan DTH,(2000) Risk factors for the development of pterygium in singapore: a hospital based case control study - : Acta Ophthalmol Scand

Girolamo ND, Chui J, Coroneo MT,(2004) Pathogenesis of pterygia: role of cytokines, growth factors, and matrix metalloproteinases - : Progress in retinal and eye research

Detorakis ET, Spandidos DA,(2009) Pathogenetic mechanism and treatment options for ophthalmic pterygium: Trends and perspectives (Review) - : International journal of molecular medicine





Archive Article

Cover Media Content

Volume : 7 / No. : 5 / Pub. : 2011-06
  1. Limbal Dermoid And Pre-auricular Tag In A 12 Years Old Girl
  2. Vitrectomy And Silicone Oil Tamponade In The Management Of Retinal Detachment In Marfan Syndrome Patient
  3. Crouzon Syndrome
  4. Histopathologic Profile Grading Of Haematoxylene Eosin On Retinoblastoma Stadium
  5. Decrease Of Corneal Sensitivity In Patients With Diabetes Mellitus Type Ii
  6. Glaucoma Caused Blindness With Its Characteristic In Cipto Mangunkusumo Hospital
  7. Visual Field Abnormality And Quality Of Life Of Patient With Primary Open Angle Glaucoma
  8. The Role Of Ascorbic Acid On Endothelial Cell Damage In Phacoemulsification
  9. The Risk Factors Of Human Papilloma Virus 18 On The Recurrences Of Pterygium
  10. Crouzon Syndrome

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