UNIVERSITAS AIRLANGGA



Detail Article

Majalah Ilmu Faal Indonesia

ISSN 0215-1995

Vol. 11 / No. 2 / Published : 2016-09

Order : 2, and page :64 - 66

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Original Article :

Dynamic eccentric exercise improve glut-1 expression on calf muscle of diabetic mice models

Author :

  1. Bambang Purwanto*1
  2. Gadis Meinar Sari*2
  3. Tjitra Wardani*3
  1. Dosen Fakultas Kedokteran
  2. Dosen Fakultas Kedokteran
  3. Dosen Fakultas Kedokteran

Abstract :

Introduction.Previous study we found that Glut-1 was also expressed on calf muscle of diabetic mice models. Exercise was known as one of diabetic modalities therapy but itwas still unclear whether exercise improved Glut-1 expression on diabetic muscle. Purpose. This study was aimed to investigate the effect of dynamic eccentricexercise on Glut-1 expression. Methode. Multiple low dose of streptozotocin administration was used to induce diabetes at mice.Diabetic mice were run on treadmill with negative inclination (downhill) for 21 minutesas dynamic model of eccentric exercise for calf muscle. Results. A significant improvement ofGlut-1 expression found optimal at -5 degree of declined treadmill. Conclusion. Eccentric exercise improves Glut-1 expression and proposed as an alternative mechanism explained the benefit of exercise on diabetes therapy

Keyword :

eccentric, downhill, Glut-1, diabetes, exercise,


References :

Bubbico, A. and Kravitz, L,(2010) Eccentric Exercise: A Comprehensive Review of a DistinctiveTraining Method Vol. 7 No. 9, pp. 50-59 : IDEA Fitness Journal

Chambers M.A., Moylan, J.S., Smith, J.D., Goodyear, L.J., and Reid, M.B,(2009) StretchStimulated Glucose Uptake in Skeletal Muscle is Mediated by ROS & p38 MAPK Vol. 587, pp. 3363-3373 : TheJournal of Physiology





Archive Article

Cover Media Content

Volume : 11 / No. : 2 / Pub. : 2016-09
  1. A Function Discriminate The Risk Of Type 2 Diabetes Among Indonesian Obese Characteristics
  2. Dynamic Eccentric Exercise Improve Glut-1 Expression On Calf Muscle Of Diabetic Mice Models
  3. Effects Of Tumeric Ethanol Extract (curcuma Domestica Val) To Prevent Ulcus Pepticum Which Induced By Histamin
  4. Effect Of Caffeine On Endurance Duration Of Student Using Graded Exercise Test
  5. Effects Of Glutathione Protection Against Erythrocytes Post Submaximal Physical Exercise On Rat (rattus Norvegicus) Males
  6. Administration Of Sembukan’s Leaves Extract Improve Blood Glucose Level In Diabetes Mellitus Animal Model
  7. Supplementation Of Saturated Fatty Acid, Mono Unsaturated Fatty Acid, And Poly Unsaturated Fatty Acid: Triglyceride Comparison Study On White Rat (rattus Norvegicus)
  8. Comparison Of Lumbar Flexibility And Hamstring Muscles Shortening In Full Day And Non Full Day Students
  9. Correlation Between Body Mass Index With Physical Fitness Student Of Airlangga University
  10. The Effects Of Interval Training On Slowing Of Weight Gain And Lowering Lee Index Scoring In An Obese Rats Model

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