UNIVERSITAS AIRLANGGA



Detail Article

Majalah Ilmu Faal Indonesia

ISSN 0215-1995

Vol. 8 / No. 1 / Published : 2008-10

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Original Article :

Efektifitas garam lososadalam menghambat peningkatan peroksida lipid

Author :

  1. S Andhi Jusup*1
  1. Departemen Ilmu Faal Fakultas Kedokteran Universitas Negeri Solo Surakarta
    Jalan Ir. Sutami 36 A, Solo, 57126, Jateng

Abstract :

The aim of this research was to evaluate the effectivity of LOSOSA salt on inhibiting the increasing of lipid peroxidation especially in higher dose. The lipid proxidation was measured on the level of MDA plasma. 32 Sprague Dawly Rat aging 4 months, were divided randomly into 4 group. Group A as kontrol group was given High Sodium solution/HS ( 8% Nacl), Group B was given LOSOSA 8%, Group C was given LOSOSA 12%, and Group D was given LOSOSA 16%. The data was analyzed statistically to evaluate the effectivity of LOSOSA on inhibiting the increasing of lipid peroxide. The high increasing of MDA plasma level occurred on control/HS group ( 8,24  0,38 mmol). While the increasing of MDA plasma level on B,C and D group only 0,21  0.08 mmol; 0,50  0,16 mmol; and 3,93  0,37 mmol. The increasing of MDA plasma level on three groups of LOSOSA were different significantly (p < 0,05) in comparing with control/HS group. LOSOSA salt was effective on inhibiting the increasing of lipid perokside , although at higher dose (up to twice).

Keyword :

Lososa, MDA (Malonyldialdehyde),


References :





Archive Article

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Volume : 8 / No. : 1 / Pub. : 2008-10
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