Majalah Ilmu Faal Indonesia
ISSN 0215-1995
Vol. 11 / No. 2 / Published : 2016-09
Order : 3, and page :67 - 71
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Original Article :
Effects of tumeric ethanol extract (curcuma domestica val) to prevent ulcus pepticum which induced by histamin
Author :
- Nugroho*1
- Gwenny Ichsan Prabowo*2
- Indri Safitri Mukono*3
- Dosen FK Universitas Wijaya Kusuma
- Dosen Fakultas Kedokteran
- Dosen Fakultas Kedokteran
Abstract :
Gastric ulcer is one of the increase gastric acid causes which mediated by H2 reseptor. Tumeric is extracted using the ethanol 96% and it is tested using Rattus norvegicus Wistar strain to know the effect as anti gastritis. Based on that, we want to study whether tumeric can be use as gastric protective by looking at atmicroscopic image of gastric. Male Wistar rats were divided into five groups : 1) NaCMC control group, 2) CMC-Na io histamine plus 300 mg/kg ip groups, 3) three groups ethanol turmeric diferent io histamine plus 300 mg/kg ip treated groups, Rats were sacrified at 6 h after injection of histamine, and stomach tissues were harvested for making histopathologic slides. Ethanol extract of tumeric decrease incidence and preventable for ulcus gastric causes by histamin.
Keyword :
Ethanol tumeric extract, histamine, free acid, total acid, organic acids,
References :
Anderson,(1990) Treat¬ment of stomach disease, AThai medicinal plant of new selection for you. Medicinal Plant Project for Self Reliance, 2nd edition 1-100 (in Thai) : Bangkok: Edison Press Product
Araujo , Leon,(2001) Gastroprotective activity of ginger, Zingiber officinale rose 1-6 : American Journal of Chinese Medicine
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