Majalah Ilmu Faal Indonesia
ISSN 0215-1995
Vol. 5 / No. 1 / Published : 2005-10
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Original Article :
Pengaruh asam askorbat terhadap kadar imunoglobulin a sekretori pada saliva
Author :
- Aqsa Sjuhada Oki*1
- Sunarko Setyawan*2
Abstract :
Salivary secretory imunoglobulin A (IgA) is critical component in oral immune system It inhibit microbal adherence, inactivate bacterial enzyme and toxin, and neutrilize virus. Number of oral diseases are associated with Salivary secretory imunoglobulin A, sub. As caries and periodontal disease. The effect of ascorbic acid on salivary secretory imunoglobulin A have been studied. This research observed the chromatographical expressión of salivary secretory imunoglobulin A using ELISA method. The animal model was Rattus novergicus strain Sprague–Dawley. The number of the subjects was 30 and divided into three groups. Each group had ten rats. Group I was the placebo group. In the second and third group the animals received ascorbic acid supplementation in the dose of 1 and 2 mg/100 g body weight per day for two weeks, repectively. After ascorbic acid supplementations were completed, we performed saliva collection procedure. The animals were injected with pilocarpine and isoproterenol to stimulate saliva secretion. The analytical test (Anova) showed significant differences between all groups on the concentration of salivary secretory imunoglobulin A in the magnitude of ug/ml. This study sugests that the supplementation of α-tocopherol and ascorbic acid may stimulate the salivary secretory imunoglobulin A
Keyword :
immunoglobulin A, saliva, ascorbic acid, ELISA,
References :
T Akimoto,(2003) Effects of 12 monts of exercise training on salivary secretory IgA levels in eldery subjects - : Br J Sports Med. 37
T Atsumi,(1999) Free radical scavenging activity in the nonenzymatic fraction of human saliva: a simple DPPH assay showing the effect of physical exercise. - : Antioxidant and Redox Signaling. 1(4)
A Balmaseda,(2003) Diagnosis of dengue virus infection by detection of specific immunoglobulin M (IgM) and IgA antibodies in serum and saliva. - : Clinical and Diagnostic Laboratory Immunology. Mar
C Delporte,(1997) Increased fluid secretion after adenoviral-mediated transfer of the aquaporin-1 cDNA to irradiated rat salivary glands. - : Proc.Natl.Acad.Sci. 94
T Godfrey,(1997) The effect of vitamin c supplementation on performance of neonatal dairy calves and the incidence of diarrhea. Final Repaort, unpublished data - : -
T Godfrey,(1997) The effect of vitamin c supplementation on performance of neonatal dairy calves and the
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 Volume : 5 / No. : 1 / Pub. : 2005-10 |
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