Majalah Ilmu Faal Indonesia
ISSN 0215-1995
Vol. 7 / No. 2 / Published : 2008-02
Order : 2, and page :82 - 85
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Original Article :
Potensi melatonin secara fotoneuroendokrin sebagai antioksidan alamiah
Author :
- Ratna Damayanti*1
- Anwar Ma’ruf*2
- Kuncoro Puguh Santoso*3
- Nove Hidajati*4
- Bagian Fisiologi Veteriner Departemen Ilmu Kedokteran Dasar Veteriner
Fakultas Kedokteran Hewan Universitas Airlangga,Surabaya - Dosen Fakultas Kedokteran Hewan
- Bagian Fisiologi Veteriner Departemen Ilmu Kedokteran Dasar Veteriner
Fakultas Kedokteran Hewan Universitas Airlangga,Surabaya - Departemen Biokimia Veteriner Departemen Ilmu Kedokteran Dasar Veteriner Fakultas Kedokteran Hewan Universitas Airlangga, Surabaya
Abstract :
The objective of this study was to identified improvement mechanism of antioxidant; melatonin, with photoendocrine signed by decreasing level of malondialdehide (MDA). Hopefully this finding will be basic of natural antioxidant making process. This research using Pre-Post Test Design. Sample are 40 male rabbits, 5 months old divided into 5 groups . Rabbit in group A without lighting, group B with 3 hours lighting, from 18.00-21.00WIB, goup C with 6 hours lighting from 18.00- 24.00 WIB, group D with 12 hours lighting from 18.00-06.00WIB, group E with 24 hours lighting from 18.00-18.00 WIB in the next day. This treatment was done in 30 days. Blood sample taken from vena auriculars before and after treatment and examined for MDA level with spectrofotometer in 529 nm wavelength. Data was analyzed by Anova 5 % and LSD test 5 %. The result showed that rabbit in group A and B have lower MDA level than in another group. In conclusion, antioxidant level will improve by minimum lighting at night
Keyword :
melatonin, antioxidant, lighting, malondialdehide (MDA),
References :
Arendt, J.,(1998) Melatonin and the pineal gland: influence on mamalian seasonal and circadian physiology - : J. Reproduction and Fertility 3, 13-22
Bartness Tj, Demas GE, Song CK,(2002) Seasonal Changes ini Adiposity: The Roles of the Photoperiod - : Nelatonin and other Hormones, and Sympathetic Nervous System Exp Biol Med
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