UNIVERSITAS AIRLANGGA



Detail Article

Majalah Obstetri & Ginekologi

ISSN 0854-0381

Vol. 16 / No. 3 / Published : 2001-01

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Original Article :

Successful management of pregestational dm with severe complications

Author :

  1. Ariefandi*1
  2. Hermanto*2
  1. -
  2. -

Abstract :

Pregestational diabetes mellitus is one of the most frequent medical complications in pregnancy. Compared with gestational diabetes, there are and organs complications, easiness to get the complications and more difficulties in glucose regulation . Team work, intensive monitoring and adequate facilities needed to manage this case appropriately. Here we present two cases of pregestational diabetes with severe end organ complications i.e. retinopathy, nephropathy and chronic hypertension. Even in literature study stated that there are infertility in women with diabetes but only 1 case with difficulty to get pregnant. From laboratory examination, the glucose levels were 210–220 mg/dl and Hb A1C 8% and 7,5% – a little bit higher. Maintaining appropriate blood glucose level, managing the complications and decided the timely delivery of the baby were the main problems. Diet, and some insulin combinations were used accordingly. Termination of the pregnancy were done with maternal indications severe preeclampsia; cesarean delivery were performed, 1 suffered from IUGR and 1 suffered from DKA. Intensive care by 1 team delivered to the mother and newborn and both cases discharged in good conditions.  After two years the mothers were still under controlled and there were no signs of obesity and DM in the babies. Lesson learned from this report is team approach in pregestational diabetes with severe complications is mandatory due to the difficulties in maintaining the appropriate blood glucose level and decided the timely delivery of the baby. And monitoring the adult consequences of fetal programming should be done closely. As with Barker hypothesis, monitoring of both babies would be continued because the probability of metabolic disorder in these two cases were very high.

Keyword :

Pregestational diabetes mellitus, severe complication,


References :

Hermanto HT, Pranoto A,(0000) Konsensus pedoman diagnosis dan terapi diabetes melitus dalam kehamilan :

nzucchi SE, Galerneau F,(0000) :





Archive Article

Cover Media Content

Volume : 16 / No. : 3 / Pub. : 2008-09
  1. Comparison Of Neutropenia And Peripheral Neuropathy Incidence With Paclitaxel Infusion 3 Hours Vs 24 Hours In Adjuvant Therapy With Paclitaxel – Carboplatin In Ovarian Carcinoma
  2. Comparison Of Brain Derived Neurotrophic Factor (bdnf) Serum Level Of Newborn Placenta Between Pregnant Woman Either Obtained Docosahexaenoic Acid (dha) Or Not
  3. Ratio Of Bcl-2/bax Expression And The Changing Of Endometrial Gland Of Rattus Novergicus At A Model Of Pcos With Flutamide And Mpa Therapy
  4. Successful Management Of Pregestational Dm With Severe Complications
  5. A Case Of Trap Sequence At Dr. Soetomo General Hospital

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