UNIVERSITAS AIRLANGGA



Detail Article

Journal Orthopaedi and Traumatology Surabaya

ISSN 2460-8742

Vol. 7 / No. 2 / Published : 2018-10

Order : 4, and page :31 - 37

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Original Article :

Risk factors for impaired bone density in male patients underwent hemodialysis due to chronic kidney disease

Author :

  1. Patritius Kelik Dwi Santo Ismoyo*1
  2. Sugeng Yuwana*2
  1. SMF/Divisi Orthopaedi dan Traumatologi, Departemen Bedah, RSUP Dr. Sardjito/Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan, Universitas Gadjah Mada Yogyakarta
  2. SMF/Divisi Orthopaedi dan Traumatologi, Departemen Bedah, RSUP Dr. Sardjito/Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan, Universitas Gadjah Mada Yogyakarta

Abstract :

Background: Chronic kidney disease (CKD) is associated with impairment of mineral metabolism that, in turn, may result in the derangement of bone density, i.e. osteopenia or osteoporosis.   Purpose: The objective of this study is to assess the impairment of bone density in male patients underwent routine hemodialysis due to stage V CKD. Methods: Subjects in this cross sectional study were male patients underwent routine hemodialysis in Hemodialysis Unit Dr. Sardjito General Hospital Yogyakarta in June 2014. Subjects were invited when they were over 18 years old and had undergone hemodialysis for at least 6 months. Bone density of lumbar spine, total hip and femoral neck were assessed using DEXA. We collected information on age and the etiology of the CKD from medical records. Body weight and height were measured using calibrated apparatus. Data were analyzed using OpenEpi. Results: We invited 30 male patients with mean (SD) age of 56.8 (13.8) years. Bone density of lumbar spine and femoral neck were significantly associated with the duration of hemodialysis, i.e. OR (95% CI) of 31.7 (3.8-856.0), p=0.0003 and 12.0 (1.9-111.0), p=0.005, respectively for those underwent hemodialysis of more than 12 months. Obesity was only protective for the bone density of the total hip, OR(95%CI) of 0.1 (0.004-0.9), p=0.03. There was no association between the etiology of the CKD and the decrease in bone density. Conclusion: This study observed significant association between the duration of hemodialysis and bone density.

Keyword :

Chronic Kidney Disease, hemodialysis, bone mineral density, DEXA,


References :

Malluche, H.H., Porter, S., Daniel, F. M.C,(2011) Differences in Bone Quality in Low and High Turnover Renal Osteodystrophy 23: 525-32 : Kidney Int





Archive Article

Cover Media Content

Volume : 7 / No. : 2 / Pub. : 2018-10
  1. Effect Of Platelet Rich Fibrin And Mesenchymal Stem Cell On Myoblast And Fibroblasts Ratio In Rabbit Muscle Defect
  2. Relationship Of Acl Injury With Posterior Tibial Slope, Intercondylar Notch Width Ratio, Age, And Sex
  3. The Effectiveness Of Zinc And Risedronate On Bone Turnover In Rat Model Of Osteoporosis Assessed With The Expression Of β-crosslaps
  4. Risk Factors For Impaired Bone Density In Male Patients Underwent Hemodialysis Due To Chronic Kidney Disease
  5. Quality Of Life Comparation In Metastatic Bone Disease Patient Before And After Surgery In Dr. Soetomo General Hospital
  6. Analysis Of Immunity In Osteosarcoma As A Basis For Development Following Therapy

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