UNIVERSITAS AIRLANGGA



Detail Article

OVOZOA

ISSN 2302-6464

Vol. 7 / No. 1 / Published : 2018-04

Order : 10, and page :47 - 51

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Original Article :

Efek pemberian l-arginine secara oral pada spermatogenesis dan sel sertoli testis kelinci ( oryctolagus cuniculus)

Author :

  1. Hening Tyas Pitaloka*1
  2. Prof. Mas’ud Hariadi, M.Phil., Ph.D., drh*2
  3. Dr.Nove Hidajati, drh., M.Kes.*3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

L-Arginine is the precursor of  nitric oxide (NO). The aim of this research was to know the effect oral administration of L-arginine on spermatogenesis and the number of Sertoli cell of seminiferous tubules of rabbit (Oryctolagus cuniculus). This researh used sixteen  rabbits (6 months old and  ± 3 kg of  body weight) were devided into two groups, P0 and P1. P0 is a control group and P1 was given L-arginine 6g/300ml/day for 30 consecutive days. After 30 days treatment, their testicles were collected and processed for histological examination. The data were analyzed by Kruskall Wallis Test for Johnsen’s Score and ANOVA for Sertoli cells counting at the significancy level of 5%. The result from statistical analysis showed that treatment with L-arginine did not increase spermatogenesis compared with control group, while the Sertoli cells of rabbit testicular showed that L-arginine increased the number of Sertoli cells.

Keyword :

spermatogenesis, Sertoli cells, L-Arginine, nitric oxide, testis,


References :

Adams, M.R., Forsyth, C.J., Jessup, W., Robinson, J., Celermajer, D.S.,(1995) Oral L-Arginine Inhibits Platelet Aggregation but Does Not Enhance Endothelium-Dependent Dilatation in Healthy Young Men. 26: 1054-1061 : Journal of The American College of Cardiology.

Berndtson, W.E., Igboeli, G., Pickett, B.W.,(1987) Relationship of Absolute Numbers of Sertoli Cella to Testicular Size and Spermatogenesis in Youn Beef Bulls. 64: 241-246. : J. Anita. Sci.

Garg, V., Garg, S.P.,(2011) Role of Nitric Oxide in Male Infertility. 33 (1): 65-68. : Journal of Indian Academy of Forensic Medicine.

Griswold, M.D.,(1995) Interactions Between Germ Ccells and Sertoli Cells in The Testis. 52: 211-216. : Biology of Reproduction.

Griswold, M.D.,(1998) The Central Role of Sertoli Cells in Spermatogenesis. 9 (4): 411-416. : Seminars in Cell and Developmental Biology.

Jarad, A.S., Al-Samawy, E.R.M., Al-Badran, A.S.H.,(2011) Effect of L-Arginine on Spermatogenesis of The Diabetic



Archive Article

Cover Media Content

Volume : 7 / No. : 1 / Pub. : 2018-04
  1. Efisiensi Reproduksi Sapi Perah Peranakan Friesian Holstein (pfh) Akseptor Inseminasi Buatan (ib) Di Kud Sri Wigati Kecamatan Pagerwojo Kabupaten Tulungagung
  2. Efisiensi Reproduksi Sapi Perah Di Kecamatan Cendana Kabupaten Enrekang Sulawesi Selatan
  3. Pengaruh Penambahan L-arginin Pada Media Pengencer Skim-kuning Telur Terhadap Membran Plasma Dan Tudung Akrosom Spermatozoa Domba Merino Post Thawing
  4. Pengaruh Pemberian Beras Merah (oryza Nivara) Dibandingkan Beras Putih (oryza Sativa) Terhadap Jumlah Anak Dan Bobot Lahir Anak Mencit (mus Musculus) Sekelahiran Yang Hidup
  5. Analisis Kadar Kalsium (ca) Dan Fosfor (p) Serum Sapi Perah Penderita Milk Fever Di Wilayah Kerja Kpsp Setia Kawan Kecamatan Tutur Pasuruan
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  8. Potensi Ekstrak Etanol Seledri (apium Graveolens) Terhadap Diameter Tubulus Seminiferus Dan Jumlah Sel Spermatogenik Mencit (mus Musculus)
  9. Penambahan Sari Air Laut (nigarin) Dalam Pengencer Skim Kuning Telur Terhadap Viabilitas Dan Motilitas Spermatozoa Sapi Limousin Post Thawing
  10. Efek Pemberian L-arginine Secara Oral Pada Spermatogenesis Dan Sel Sertoli Testis Kelinci ( Oryctolagus Cuniculus)
  11. Efisiensi Reproduksi Sapi Peranakan Ongole (po) Dan Persilangan Limousin-po (limpo) Hasil Inseminasi Buatan Di Kecamatan Paciran Kabupaten Lamongan
  12. Pengaruh Sari Kulit Dan Buah Semangka Merah (citrullus Lanatus) Sebagai Bahan Pengencer Terhadap Motilitas Dan Viabilitas Spermatozoa Domba
  13. Pengaruh Penambahan L-arginin Dalam Pengencer Susu Skim Kuning Telur Terhadap Motilitas Dan Viabilitas Spermatozoa Domba Merino Post Thawing
  14. Efisiensi Reproduksi Sapi Perah Hasil Inseminasi Buatan Di Kecamatan Sanankulon Kabupaten Blitar Pada Tahun 2015
  15. Efek Protektif Aluminium Silikat Terhadap Kualitas Spermatozoa, Integrasi Membran Plasma Dan Gambaran Histopatologis Tubulus Seminiferus Yang Diinduksi Fusarium Graminearum Pada Mencit Jantan (mus Musculus)
  16. Substitusi Pakan Isi Rumen Sapi Sebagai Alternatif Perbaikan Produktifitas Ternak Itik Mojosari Di Desa Kebonsari Kecamatan Candi Sidoarjo

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