UNIVERSITAS AIRLANGGA



Detail Article

OVOZOA

ISSN 2302-6464

Vol. 4 / No. 1 / Published : 2015-04

Order : 6, and page :24 - 28

Related with : Scholar   Yahoo!   Bing

Original Article :

Perubahan histopatologi jaringan interstitial testis tikus putih (rattus norvegicus) yang dipapar boraks (na2b4o7.10h2o)

Author :

  1. Ririn Rohmawati*1
  2. Dr. Rimayanti., drh., M.Kes*2
  3. Suryo Kuncorojakti, drh., M.Vet*3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

The aim of this study was to evaluate the histopatological of testis interstitial tissue due to treatment of borax for 14 days. Twenty male rats (Rattus norvegicus) aged 2 months with body weight 100 gram were used in this study. The rats were devided into four groups (P0, P1, P2, and P3).  P0 was the control group which  treated by sterile aquadest 0,5 ml/rats/day (without borax), P1 group was treated  19 mg borax/rats/day, P2 group was treated  26 mg borax/rats/day, P3 group was treated with 37 mg borax/rats/day. The data were analyzed by using ANOVA test and Duncan  test. The result of this study showed that the number of Leydig cell  decreased, necrosis cell Leydig increased and there was hemodynamic disorder (congesti and oedema) at wistar rat testis interstitial tissue.

Keyword :

Rattus norvegicus, Boraks, Interstitial Tissue, Leydig Cell,


References :

Chapin, R.E. and Ku, W.W. ,(1994) Mechanism of the testicular toxicity of boric acid in rats: in vivo and in vitro studies. 102: 99-104. : Environmental Health Perspective.

Dourson, M., A. Maier, B. Meek, F., Bareille, R., Baquey. ,(2003) Boron tolerable intake re-evaluation of toxicokinetics for data derived uncertainty factors. 66: 453-463. : Biol. Trace Elem. Res.

Leichtnam, M.L., Rolland, H., Wuthrich, P., Guy, R.H. ,(2006) Testosterone hormone replacement therapy: stateof- the-art and emerging technologies. 23: 1123-1125. : Pharmaceutical research.

Wery, N., Narotsky, M., Pacico, N. ,(2003) Defects in cervical vertebrae and spleen in boric acid-exposed rat embryos are associated with anterior shifts of hox gene expression domains. 67:59-67. : Birth Defects Res (Part A)





Archive Article

Cover Media Content

Volume : 4 / No. : 1 / Pub. : 2015-04
  1. Boraks Mengakibatkan Penurunan Jumlah Sel Spermatogonium Dan Sel Sertoli Pada Gambaran Histopatologi Testis Tikus Putih (rattus Norvegicus)
  2. Kadar Progesteron Serum Domba Ekor Gemuk Sebelum Pemasangan Dan Sesudah Pencabutan Implan Progesteron Subkutan
  3. Pemberian Injeksi Kombinasi Hormon Pmsg Dan Hcg Terhadap Waktu Timbulnya Birahi Pada Sapi Madura Di Desa Sembilangan Kecamatan Bangkalan Kabupaten Bangkalan
  4. Pengaruh Pemberian Infusa Kulit Manggis (garcinia Mangostana L.) Terhadap Peningkatan Persentase Kapasitasi Spermatozoa Tikus Putih (rattus Norvegicus)
  5. Pengaruh Pemberian Infusa Kulit Manggis (garcinia Mangostana L.) Terhadap Motilitas, Viabilitas Dan Integritas Membran Spermatozoa Tikus Putih (rattus Norvegicus)
  6. Perubahan Histopatologi Jaringan Interstitial Testis Tikus Putih (rattus Norvegicus) Yang Dipapar Boraks (na2b4o7.10h2o)
  7. Waktu Inseminasi Buatan Pada Sapi Perah Yang Digertak Birahi Dengan Hormon Prostaglandin F2α Dan Hormon Gonadotropin
  8. Isolasi Dan Karakterisasi Fertility Associated Antigen (faa) Dalam Membran Spermatozoa Sebagai Bahan Aktif Kesuburan Spermatozoa Sapi
  9. Perbedaan Non Return Rate (nrr) Hari Ke 21 Dan Conception Rate (cr) Hari Ke 75 Sapi Perah Yang Disinkronisasi Birahi Menggunakan Prostaglandin F2α (pgf2α) Dengan Gonadotropin (kombinasi Pmsg Dan Hcg)
  10. Pengujian Kualitas Semen Segar Kambing Gembrong Untuk Proses Pembekuan Di Teaching Farm
  11. Pengaruh Waktu Equilibrasi Terhadap Motilitas Dan Viabilitas Spermatozoa Kambing Gembrong Post Thawing Dalam Pengencer Skim Kuning Telur
  12. Nilai Bod (biochemical Oxygen Deman) Dan Cod (chemical Oxygen Deman) Air Kolam Dan Limbah Usaha Perikanan Yang Menggunakan Kotoran Bebek Sebagai Media Budidaya Ikan Lele
  13. Pemeriksaan Kadar Hormon Estrogen Sebagai Indikator Diagnostik Adanya Kebuntingan Dini Pada Kuda Poni
  14. Pengaruh Berbagai Konsentrasi Kuning Telur Itik Dalam Susu Skim Sebagai Pengencer Semen Domba Ekor Gemuk Terhadap Motilitas, Viabilitas Dan Keutuhan Membran Plasma Spermatozoa Before Freezing

Information index.php/JIPK/OVOZOA