UNIVERSITAS AIRLANGGA



Detail Article

Planta Husada

ISSN 2338-7130

Vol. 1 / No. 1 / Published : 2013-10

Order : 2, and page :4 - 6

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Original Article :

Hypoglycemic activity herbal tea combination of andrographis paniculata herbs and swietenia mahagoni seeds

Author :

  1. Sukardiman*1
  2. Abdul Rahman*2
  3. Herra Studiawan*3
  4. Mulja Hadi S*4
  5. Aty Widyawaruyanti*5
  6. Rizal Firdaus*6
  1. Dosen Fakultas Farmasi
  2. Dosen Fakultas Farmasi
  3. Dosen Fakultas Farmasi
  4. Dosen Fakultas Farmasi
  5. Dosen Fakultas Farmasi
  6. Mahasiswa Fakultas Farmasi

Abstract :

Hypoglycemic Activity Herbal Tea Combination of Andrographis paniculata Herbs and Swietenia mahagoni Seeds  Sukardiman*), Rizal Firdaus, Aty Widyawaruyanti, Herra Studiawan, Mulja Hadi S., Abdul Rahman  Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy Universitas Airlangga, Surabaya, Indonesia.  *)email : maman_ht@yahoo.com   Diabetes mellitus is a chronic metabolic disorder that continues to present a major world wide health problem. Numerous herbal drugs like Andrographis paniculata and Swietenia mahagoni have been used by people of various cultures to treat diabetes. The aim of this research was to measure the hypoglycemic activity herbal tea of Andrographis paniculata herbs and Swietenia mahagoni seeds and their combination in alloxan-induced diabetic mice. The tea was prepared by brewing 10 g herbal tea with 100 ml of boiling water for 10 minutes. The herbal tea of Andrographis paniculata herbs, Swietenia mahagoni seeds, combination with ratio 1:1, 1:2 and 2:1 (0.4 ml/20 g BW), was administered orally to groups I, II, III, IV and V respectively. The reference drug glibenclamide (0.013 mg/10 g BW) and CMC-Na were also administered orally to animals in positive and negative control group respectively. Oral administration of herbal tea for seven days resulted in a slight reduction in blood glucose level. Statistically there is no groups that has significant difference with negative control groups (P < 0.05) except positive control. Therefore the herbal tea combination of Andrographis paniculata herbs and Swietenia mahagoni seeds with ratio 2:1, showed the biggest reduction in blood glucose level (88.20 ± 43.16 mg/dl).

Keyword :

Andrographis paniculata, Swietenia mahagoni, hypoglycemic activity, Herbal tea,


References :

Akbar S,(2011) Andrographis paniculata: A Review of Pharmacological Activities and Clinical Effects - : Alternative Medicine Review

Debasis et al.,(2011) Antidiabetic Potentiality of the Aqueous-Methanolic Extract of Seed of Swietenia mahagoni (L.) Jacq. In Streptozotocin-Induced Diabetic Male Albino Rat: A Correlative and Evidence-Based Approach with Antioxidative and Antihyperlipidemic Activities - : Evidence-Based Complementary and Alternative Medicine

Dipiro et al.,(2008) Pharmacotherapy: A Patophysiologic Approach, 7th Edition New York : Mc Graw Hill

Preedy et al.,(2011) Nuts and Seeds in Health and Disease Prevention UK : Academic Press

Suherman KH dan Nafrialdi,(2011) Insulin dan Antidiabetik Oral. Farmakologi dan Terapan edisi 5 Jakarta : Balai penerbit FKUI





Archive Article

Cover Media Content

Volume : 1 / No. : 1 / Pub. : 2013-10
  1. Hypoglycemic Activity Of 96% Ethanolic Extract Of Andrographis Paniculata Nees. And Swietenia Mahagoni Jacq. Combination.
  2. Hypoglycemic Activity Herbal Tea Combination Of Andrographis Paniculata Herbs And Swietenia Mahagoni Seeds
  3. Hypoglycemic Activity Of Andrographis Paniculata Nees. And Lagerstroemia Speciosa L. Herbal Tea Combination
  4. ¬hypoglycemic Activity Of The Herbal Tea Combination Of Bitter Melon (momordica Charantia L.) And Lagerstroemia Speciosa Leaves In Alloxan-induced Mice
  5. Hypoglycemic Effect Of Andrographis Paniculata Nees And Lagerstroemia Speciosa Extract Combination

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