UNIVERSITAS AIRLANGGA



Detail Article

Jurnal Psikiatri Surabaya

ISSN 2355-2409

Vol. 4 / No. 1 / Published : 2015-04

Order : 5, and page :52 - 64

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Original Article :

Long-acting antipsychotic injection for schizophrenia treatment

Author :

  1. Aimee Nugroho*1
  2. Soetjipto*2
  1. Mahasiswa Fakultas Kedokteran
  2. Dosen Fakultas Kedokteran

Abstract :

Medication nonadherence has been associated with persistence of psychotic symptoms, relapse, andhospitalization in patients with schizophrenia. Patients with untreated psychosis are significantly less likely to achieve remission, whereas antipsychotic drug adherence has been associated with recovery. As such, adherence to antipsychotic drug treatment is a key issue for psychiatrists caring for patients who typically are on a chronic, progressive disease course. Long-acting antipsychotic injection (LAI) drugs, developed to improve adherence and provide an alternative antipsychotic drug treatment for schizophrenia, have been associated with improved treatment outcomes including reduction of relapse rates by approximately 30% and reduction in hospitalizations. However, LAI antipsychotic drugs remain underutilized  despite a growing body of literature supporting positive outcomes of LAI versus oral antipsychotic drugs. Psychiatrists are in a key position to support improved adherence in patients with schizophrenia through use of practical educational strategies that help patients, family members, and health care providers better understand and manage treatment.

Keyword :

Long-acting Antipsychotic Injection, Schizophrenia,


References :

Abbott C, Keith S. ,(2011) Antipsychotic Treatment and Adherence in Schizophrenia. Antipsychotic Long- acting Injections 1-22. : Oxford University Press, United Kingdom,





Archive Article

Cover Media Content

Volume : 4 / No. : 1 / Pub. : 2015-04
  1. End Life Care In Terminaly Ill Patients Focusing On Spirituality
  2. Family Focused Treatment For Adolescents With Bipolar Disorder
  3. Psychopathology And Psychiatric Problems In Burn Injury
  4. Schizo-obsessive Disorder
  5. Long-acting Antipsychotic Injection For Schizophrenia Treatment
  6. Family Therapy In Schizophrenia (focused On Psychoeducational Model)
  7. Parenting Style And Child Psychosocial Factors As Predictors Of Mental Emosional Problems In Hiv/aids Infected Children