UNIVERSITAS AIRLANGGA



Detail Article

Jurnal Psikiatri Surabaya

ISSN 2355-2409

Vol. 3 / No. 1 / Published : 2014-04

Order : 1, and page :1 - 10

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Original Article :

Prenatal factors on schizophrenia

Author :

  1. Nevi Hidayati*1
  2. Nining Febriyana*2
  1. Mahasiswa Fakultas Kedokteran
  2. Dosen Fakultas Kedokteran

Abstract :

Schizophrenia is a chronic severe mental disorder with poor prognosis, and lifelong health, social, and financial burden. To the recent time, scientists still try to understand the etiologic mechanism of the disorder. Neurodevelopmental theory emerged as a model to explain the etiologic mechanism of schizophrenia.  In the view of neurodevelopmental model, genetic and environmental risk factor of schizophrenia operate in prenatal periode, interfere in  early development  process of the central nervous system and emerge symptoms later in life. Known environmental factors in prenatal periode  that increase risk of schizophrenia are gestational diabetes, fetal growth retardation, rhesus incompatibility, preeclampsia, perinatal bleeding, some birth complication caused hipoxia, infections, nutritional disturbance, and maternal stress. Searching how prenatal factors work, would be a valuable contribution to understanding schizophrenia, and establishing a proper treatment, and posible prevention strategies in the future.

Keyword :

Schizophrenia, prenatal factor, neurodevelopmental,


References :

Abel K.M., Wicks S., Susser E.S., Dalman C., Pedersen M.G., Mortensen P.B., Webb R.T.,(2011) Birth Weight, Schizophrenia, and Adult Mental Disorder, Is Risk Confined to the Smallest Babies? www.archgenpsychiatry.com : Arch Gen Psychiatry. Vol 67(9) 2010. P 923-930.

Almeras L., Eyles D., Benech P., Laffite D., Villard C., Patatian A., Boucraut J., Mackay-Sim A.,,(2012) Developmental Vitamin D Deficiency Alters Brain Protein Expression in The Adult Rat: Implications for neuropsychiatric disorders www.proteomics-journal.com : Proteomics 7 2007. P 769–780.

Brown A.S., Susser E.S. ,(2012) Prenatal nutritional deficiency and adult schizophrenia. schizophreniabulletin.oxfordjournals.org : Schizophrenia Bulletin. 34, 1054-1063 2008





Archive Article

Cover Media Content

Volume : 3 / No. : 1 / Pub. : 2014-04
  1. Prenatal Factors On Schizophrenia
  2. Biomedic Aspect On Autism Focused To Diet And Nutrition
  3. Cognitive Adaptation Training (cat) On Schizophrenia
  4. Neuropsychiatric Aspect Of Mild Cognitive Impairment (mci)
  5. Learning About Reality Therapy
  6. Terapi Elektro Konvulsi (tek)
  7. Compulsive Sexual Behaviour
  8. Correlation Between Social Support With Caregiver Burden In Wives Of Patients With Chronic Kidney Disease Within Hemodialysis Therapy In Rsud Dr Soetomo Surabaya (research)

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