Jurnal Rekonstruksi & Estetik
ISSN 2301-7937
Vol. 1 / No. 1 / Published : 2012-07
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Original Article :
Kasabach-merritt syndrome
Author :
- Lynda Hariani*1
- David S Perdanakusuma*2
- Mahasiswa
- Dosen
Abstract :
Kasabach-Merritt Syndrome is defined by a huge haemangioma with trombocytopenia dan consumption koagulopathy due to endothelial defects within the haemangioma causing platelet activation, platelet-fibrin thrombosis formation, consumption of clotting and coagulation factors, and increased fibrinolysis. The high mortality associated with this condition is often due to massive haemorrhage into lession, or elsewhere. Kasabach-Merritt syndrome shows wide variation in its response to different treatment modalities. Different interventions are recommended including compression, embolization, use of interferon, use of steroids, laser therapy, sclerotherapy, chemotherapy, radiation or surgery. The angiogenetic character of Kasabach-Merritt syndrome indicates that chemotherapy is a logical treatnent
Keyword :
Kasabach-Merritt Syndrome, chemoteraphy,
References :
William EF et al,(2000) Haemangioma in lnfant and Children : An Algoritma for Intervention Inggris : Arch Facial Plast Surg
Hall GW, Magss PHBB, Hann IM,(2000) Kasabach-Merritt syndrome: caveats of Diagnosis and Management Inggris : Current Paediatrics
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