UNIVERSITAS AIRLANGGA



Detail Article

Veterinaria Medika

ISSN 1979-1305

Vol. 3 / No. 1 / Published : 2010-02

Order : 8, and page :41 - 44

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Original Article :

Addition time interval effect of temu ireng (curcuma aeruginosa roxb.) extract to male mice (mus musculus) liver histopathological description

Author :

  1. Eka Pramyrtha Hestianah*1
  2. Nur Hidayat*2
  3. Setiawan koesdarto*3
  1. Fakultas Kedokteran Hewan Universitas Airlangga
  2. PPDH Fakultas Kedokteran Hewan Universitas Airlangga
  3. Fakultas Kedokteran Hewan Universitas Airlangga

Abstract :

The experiment was conducted to evaluated addition time interval effect of Curcuma aeruginosa Roxb.extract to the liver histopathological description of Mus musculus. Thirty five male Mus musculus were randomlydevide into seven groups and five replications each group. The control group (P0) were added 0,5 ml CMC suspention0,5% for 30 days orally. The other threatments were added with the same dose 32,5 mg/day/kg BW but with differenttime interval, P1 for 5 days, P2 for 10 days, P3 for 15 days, P4 for 20 days, P5 for 25 days and P6 for 30 days. The liverwere removed four hour after the last added of Curcuma aeruginosa Roxb. extract by necropsy. The liver was proced ashistopathological slide and staining with Haematoxyllin Eosin to examined with light microscope. The data wasanalyzed by Kruskal-Wallis test and continued Z 5% test. The result of the experiment showed that the change ofhistopathological description of liver were significantly different (p<0,05) in each group. Addition of the suspentionCurcuma aeruginosa Roxb. extract during five day had caused change of histopathological description such ascongesty and degeneration in low degree defect. If added in a longer time caused more serious defect such as congesty,degeneration and necrosis in a moderate to high degree defect.

Keyword :

Curcuma aeruginosa Roxb, extract, liver, histopathological description, .,


References :

Azmijah, A., Arimbi dan Widiyatno, T,(1996) Pengamatan Histopatologi Hati dan Ginjal Tikus Putih Akibat Pemberian Air Sumur Pada Daerah Pemukiman di Sekitar Pabrik Baja Surabaya : Lembaga Penelitian Universitas Airlangga

Dalimartha, S.,(2005) Temu Hitam (Curcuma aeruginosa Roxb). Atlas Tumbuhan Obat Indonesia. Jilid 3 Jakarta : Puspa Swara





Archive Article

Cover Media Content

Volume : 3 / No. : 1 / Pub. : 2010-02
  1. Apllication Of Frozen Semen Plus Tyrosine Kinase To Increased Conception Rate Of Beef Cattle
  2. Isolation, Identification And Characterization Of Inhibin B Protein Of Rattus Norvegicus Sertoli Cell Culture As Male Hormonal Contraception Candidate
  3. Protective Test Immunogenic Protein Of Outher Membrane Salmonella Pullorum Agains Broiler
  4. Profile Of Combination Ketamin Xylazine And Ketamin Midazolam Toward Physiologycal Change In Male Rabbit
  5. The Feed's Potential As The Contamination Source Of Aspergillus Spp. Which Caused Aspergillosis On Fowl
  6. Metabolic Product Rumen Fluid Of Sheep Which Given Lactic Acid Bacteria Suspension And Yeast On King Grass And Rice Straw
  7. Addition Time Interval Effect Of Temu Ireng (curcuma Aeruginosa Roxb.) Extract To Male Mice (mus Musculus) Liver Histopathological Description
  8. Path Analysis Of Mastitis On Dairy Cows At Cooperative Dairy Farm In Pasuruan, East Java
  9. Viability And Motility Muscovy Drake's (cairina Moschata) Spermatozoa In A Diluter Combination Of Skim Milk, Fructose And Egg Yolk
  10. Addition Of Growth Differentiation Factor-9 (gdf-9) At Culture Medium In Vitro On Chromosome Profile Of Bovine's Oocyte
  11. The Potency Of A Black Soybean Milk And Yellow Soybean Milk On The Level Of Triglycerides In Rat (rattus Novergicus) Fed With A High Fat Diet
  12. The Effect Of Centrifugation On Quality Of Motility, Viability And Acrosom Cap Of Goat Sperm
  13. Benzopyrene Induce Apoptosis Of The Lung Cells In Ratus Norvegicus
  14. Partenogenetik Development Of Mouse Oocytes Activation Using Ethanol And 6-dmap By In Vitro
  15. Identification Of Pregnancy Specific Protein B (pspb) From Placenta Foetalis (cotyledon) Freishian Holstein Cows

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