Veterinaria Medika
ISSN 1979-1305
Vol. 3 / No. 1 / Published : 2010-02
Order : 5, and page :23 - 30
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Original Article :
Profile of combination ketamin xylazine and ketamin midazolam toward physiologycal change in male rabbit
Author :
- Ira Sari Yudaniayanti*1
- Erfan Maulana*2
- Anwar Ma'ruf*3
- Fakultas Kedokteran Hewan Universitas Airlangga
- PPDH Fakultas Kedokteran Hewan Universitas Airlangga
- Fakultas Kedokteran Hewan Universitas Airlangga
Abstract :
This research were observed the comparison between combination of ketamin-xylazine and ketaminmidazolamas general anaesthesia toward heart beat, respiratory rate and body's temperature in male rabbit. Eighteenhealthy adult male rabbit about 5-6 month old with 1,5-2 kilogrames (kg) average body weight (BW) were used astested animals. This rabbit randomly divided into one of two groups. Group one (P1) had been injected using atropinesulfas (0,05 mg/kg BW) subcutan (SC) for premedication and induce by ketamin (25 mg/kg BW) - xylazine (3 mg/kgBW) intramuscular (IM) as anaesthesia. Group two (P2) had been injected using atropine sulfas(0,05 mg/kg BW) SC aspremedication and induce ketamin (25 mg/kg BW) - midazolam (2 mg/kg BW) IM as anaesthesia. Heart beat,respiratory rate and body temperature was measured before drugs were given and minutely intervals after the drugswere given (10, 20, 30, 40 and 50). The result showed that a significant difference in respiratory frequency while inheart beat frequency and body temperature, there was not a significant differences. There is a lower decreasing of P2respiration frequency than P1, regarding the heart beat and body's temperature, there was not significant differencebetween the changing that experienced by both two research's objects.
Keyword :
Anaesthesia, Ketamine, Xylazine, Midazolam, .,
References :
Frandson, R. D.,(1991) Anatomy and Physiology of Farm Animals Fort Collins, Colorado : Colorado State University
Gan, S .,(1987) Farmakologi dan Terapi Jakarta : Bagian Farmakologi, Fakultas Kedokteran, Universitas Indonesia
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