UNIVERSITAS AIRLANGGA



Detail Article

Veterinaria Medika

ISSN 1979-1305

Vol. 10 / No. 2 / Published : 2017-07

Order : 3, and page :143 - 150

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Original Article :

The influence of beta carotene to live fetus percentage in mice (mus musculus) that exposured by cigarette smoke

Author :

  1. Celica Alqurratu Rizqi*1
  2. Mas’ud Hariadi*2
  3. Sunaryo Hadi Warsito*3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

This research was conducted to observe the aplication of different doses of betacarotene toward live fetus percentage in mice (Mus musculus) that exposured by cigarretesmoke. Cigarrete smoke exposured during pregnancy can increase the levels of ReactiveOxygen Species (ROS) that disrupts the physiological maternal pregnancy and embryonicdevelopment. Beta carotene was able to reduce levels of ROS which act as antioxidants.This research was used 20 female matured mice and 20 male matured mice. Female micewere divided randomly into five groups and each got four repetitions. Each group wasused different dose. First group was negative control and used soya oil, second group waspositive control and used soya oil and one cigarette, third group was used beta carotene32,5 IU / 20 g BW in soya oil and one cigarrete, fourth group was used beta carotene 65IU / 20 g BW in soya oil and one cigarrete, fifth group was used beta carotene 130 IU / 20g BW in soya oil and one cigarrete. The experiment given per-orally of beta carotene andexposured cigarette smoke 6 – 15 pregnancy days. The data were analyzed using ANOVAand Duncan test. The result showed that aplication of beta caroten was significantlydifferent for live fetus in mice (P<0.05). Based on the research, the conclusion was thatthe oral administration of beta carotene can maintain live fetus percentage in pregnantmice (Mus musculus) that exposured by cigarette smoke.

Keyword :

Beta carotene, live fetus percentage, cigarrete smoke, ROS, .,


References :

Afonso, V. and R. Champy,(2007) Reactive Oxygen Species and Superoxide Dismutases : Role in Joint Diseases 74: 324-329 : Science direct

Agarwal, A., S. Gupta and R. K. Sharma,(2005) Role of Oxidative Stress in Female Reproduction 3 (28) : Reproductive Biology and Endocrinology

Ahsan, A., S. W. Wiyono dan W. Wibisana,(2009) Dampak Tembakau dan Pengendaliannya di Indonesia 4-80 : Lembaga Demografi FEUI





Archive Article

Cover Media Content

Volume : 10 / No. : 2 / Pub. : 2017-07
  1. Level Of Heat Shock Protein 70 And Cortisol In Bull’s Serum Before And After Collecting Semen
  2. Effectiveness Of Red Fruit (pandanus Conoideus Linn) Oil Administration On Infertile Mice (mus Musculus) Serum Luteinizing Hormone And Corpus Luteum Number
  3. The Influence Of Beta Carotene To Live Fetus Percentage In Mice (mus Musculus) That Exposured By Cigarette Smoke
  4. Immune Response Of Mice (mus Musculus) By Vaccinated Brucella Abortus Strain Rb 51 And Infected With Brucella Suis Toward Spleen Histopathology
  5. Activity Of Alkaloid Of Jarong Leaves (achyranthes Aspera Linn ) On The Death Of Cancer Cells In The Breasts Of Mice (mus Musculus)
  6. Isolation And Identification Of Edwardsiella Tarda Bacteria In Clarias Gariepinus Place Region In Jombang
  7. Effect Of Rosella Flower Extract (hibiscus Sabdariffa Linn.) On Kidney Histopathologic Of Male Mice (mus Musculus) Exposed Lead Acetate
  8. Isolation Of Keratinolytic Bacteria From Chicken Feather Waste
  9. The Pathology Of African Catfish (clarias Gariepinus) Kidney Infected By Edwardsiella Tarda
  10. Featuring Liver Pathology Of Clarias Gariepinus That Were Infected By Edwardsiella Tarda
  11. The Hepatoprotektor Activity Ofalkaloid Sambiloto Andrographis Paniculata On The Liver Cell Histopathological Changes In Male White Rat Rattus Norvegicus Induced Paracetamol Toxic Dose
  12. Acute Toxicity Test Alkaloid Fraction Of Bittermelon (momordica Charanthia L) To Histopathological Changes In The Liver And Kidneys Of Mice (mus Tmusculus)
  13. The Effects Of Vitamin C Toward Histopathology Of Stomach Of Mice Exposed To Endosulfan
  14. The Effect Of Alkaloid Achyranthes Aspera Linn On Cytochrom C And Apaf 1 Expresion On Mice Breast Cancer Was Induction By Benzopyrine
  15. Imunomodulator Potention Of Alkaloid Sambiloto (andrographis Paniculata L) To Ifnγ And Cd4+ Response After Infected By Salmonella Typhimurium On The Rat
  16. Hepatoprotector Activity Sapogenin Extract Of Sambiloto (andrographis Paniculata) 0n Alt And Ast Level On Rat Was Induction Paracetamol

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