UNIVERSITAS AIRLANGGA



Detail Article

Veterinaria Medika

ISSN 1979-1305

Vol. 9 / No. 3 / Published : 2016-11

Order : 12, and page :79 - 83

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Original Article :

Therapeutic effect rat bone marrow mesenchymal stem cell (rbm-msc) at the white rat endothelial cells induced carbon black to total hofbauer cells

Author :

  1. Bodhi Agustono*1
  2. Sri Pantja Madyawati*2
  3. Rimayanti*3
  4. Widjiati*4
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan
  4. Dosen Fakultas Kedokteran Hewan

Abstract :

The aim of this research was to prove efficacy of Rat Bone Marrow MesenchymalStem Cell (RMB-MSC) could reduce the number of Hofbauer cells of mice induced bycarbon black. This research was a experimental laboratory, with six groups of treatmentand eight times repetitions using female mice (Rattus norvegicus). The study started byfertilization of female mice following by induction with carbon black doses 532 mg/m3.In treatment’s group P1.3 and P2.3 treated with RBM-MSC doses 1x106 cells/ 0,1 mlintravenously. Following steps were observation and examination of total Hofbauer cellfrom mice placenta.The results of carbon black induction on 6-11 and 6-17 days of gestation showeddifferent the number of Hofbauer cell between control groups (P1.2 and P2.2) and treatmentgroups ( P1.1 and P2.1). Mean while in comparation between treated group with inductioncarbon black (P1.1 and P2.1) with treated group with RBM-MSC following induction ofcarbon black (P1.3 and P2.3) did not show significant difference. In summary, RBMMSCtreatment in mice on 6-11 and 6-17 day of gestation , have not supress the numberof hofbauer cell because of short time for RBM-MSC to perform optimal.

Keyword :

Carbon black, Hofbauer cell, Rat Bone Marrow Mesenchymal Stem Cell (RBM-MSC),


References :

Devries, C., J.A. Escobedo, H. Ueno, K. Houck, N. Ferrara and L.T. Wiliams. ,(1992) The fms-like tyrosine kinase, a receptor for vascular endhotelial growth factor. 225 (5047) : 989-991. : J. Science,

Elder, A., R. Gelein., J. N. Finkelstein., K. E. Driscoll., J. Harkema and G. Oberdorster. ,(2005) Effects of Subchronically Inhaled Carbon Black in Three Species. 88(2): 614–629. : Toxicological Sciences





Archive Article

Cover Media Content

Volume : 9 / No. : 3 / Pub. : 2016-11
  1. The Effect Of Spirulina Platensis Extract Immersion As Immunostimulant To Intestine Histopathology Of Aeromonas Hydrophila Infected Gouramy (osphronemus Gouramy)
  2. Effect Of Vitamin E And Vitamin C Combination As Preventive Measure On The Leydig Cell Number In Mice (mus Musculus) Treated With Borax
  3. The Influence Of Beta Carotene To Live Fetus Percentage In Mice (mus Musculus) That Exposured By Cigarette Smoke
  4. Effects Of Vitamin C And Vitamin E Combinationas Prevention On The Liver Histopathological In Mice (mus Musculus) Treated With Borax
  5. Effect Of Moringa Oleifera Leaf Extract On The Percentage Of Necrotic Purkinje Cells In Mice (mus Musculus) Induced By Methylmercury
  6. Hepatoprotective Effect Of Andrographis Paniculata Ness. Leaves Extract Towards Mice (mus Musculus L.) Liver Histopathology Which Exposured Bylead Acetate Orally
  7. The Effect Of Mimosa Pudica Root Extract To Histopathological Representation Of Rattus Norvegicus Liver Injected With Naja Sputatrix Venom
  8. Kualitas Spermatozoa Domba Merino Pada Sisi Anoda Hasil Pemisahan Dengan Teknik Ess ( Electric Separating Sperm)
  9. Effectivity Of Rat Bone Marrow Mesenchymal Stem Cell Therapy On Rattus Norvegicus Exposed To Carbon Black As Observed From Caspase-3 Expression
  10. Larvaside Effectiveness Of Srikaya Seed Extract (annona Squamosa L.) Against Mortality Of Anopheles Aconitus Larvae
  11. Therapeutic Effect Rat Bone Marrow Mesenchymal Stem Cell (rbm-msc) At The White Rat Endothelial Cells Induced Carbon Black To Total Hofbauer Cells
  12. Identification Of Bacteri Methicillin Resistent Staphylococcus Aureus And Methicillin Sensitive Staphylococcus Aureus From Dog Nasal Mucous
  13. Expression Of Cytochrome C And Capacitation Reaction Frozen Semen Fresian Holstein Bulls (fh) After Thawing In Different Temperature And Duration In Diluent Milk Egg Yolk
  14. Detection Of Bacterial Contamination Amount At Meat Which Is Soaked In Chitosan Solution With Total Plate Count Method
  15. The Effect Of Electrical Stunning On The Ph Values Musculus Fibularis Longus Broiler Chicken

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