UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 42 / No. 4 / Published : 2006-10

Order : 8, and page :249 - 255

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Original Article :

Case report: staphylococcal scalded skin syndrome in a neonate

Author :

  1. Lyly Ekawati Candra*1
  2. Fatimah Indarso*2
  3. Ismoedijanto*3
  4. Ariyanto Harsono*4
  1. Department of Pediatrics, Airlangga University School of Medicine Dr. Soetomo Teaching Hospital, Surabaya
  2. Department of Pediatrics, Airlangga University School of Medicine Dr. Soetomo Teaching Hospital, Surabaya
  3. Department of Pediatrics, Airlangga University School of Medicine Dr. Soetomo Teaching Hospital, Surabaya
  4. Department of Pediatrics, Airlangga University School of Medicine Dr. Soetomo Teaching Hospital, Surabaya

Abstract :

Exfoliative skin diseases are rare in neonates. These diseases might cause significant complications and mortality. SSSS is caused by staphylococcal exfoliative toxins A or B, which split the granular layer of the skin, induces proteolysis, and might exhibit super antigen activities, such as epidermolysis and lymphocyte mitogenicity. We describe a male neonate who developed SSSS on day 15 of life, with no clinical signs of neonatal sepsis. After cultures from the pharyngeal, conjunctivae, nasal, umbilical swab and bloodstream were obtained; intravenous cefotaxime and cloxacillin therapy were started. Infection control measures were implemented instantly and included isolation of the infected infant, personnel hand washing. Cultures from swab revealed Staphylococcus aureus, whereas the bloodstream culture revealed Pseudomonas spp. The lesions resolved completely within 2 days. No similar skin lesions were noticed in other infants in the neonatal care unit. We discuss recent advances in understanding the pathogenesis of neonatal SSSS, highlight the importance of early diagnosis and treatment, and stress the need for new adjunctive therapies for this disease.

Keyword :

4S, neonate, diagnosis, management, result,


References :

J Anjali,(1999) Staphylococcal infections in children: Part 3 no info : Pediatr Rev

RS Daum,(1999) Staphylococcal infections in children: Part 3 no info : Pediatr Rev

DM Bamberger,(2005) Management of Staphylococcus aureus Infections no info : American Academy of Family Physicians

SE Boyd,(2005) Management of Staphylococcus aureus Infections no info : American Academy of Family Physicians

S Behrman,(1991) Vesicobulous lesions Philadelphia : Decker

JP Currant,(1980) Neonatal staphylococcal scalded skin syndrome: Massive Outbreak due to an Unusual Phage Type no info : Pediatrics

FL Al-Salihi,(1980) Neonatal staphylococcal scalded skin syndrome: Massive Outbreak due to an Unusual Phage Type no info : Pediatrics

SJ Dancer,(1988) Outbreak of staphylococcal scalded skin syndrome among neonates no info : J Infect

NA Simmons,(1988) Outbreak of staphylococcal scalded skin syndrome among neonates no info : J Infect

SM Poston,(1988) Outbrea



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