UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 42 / No. 3 / Published : 2006-07

Order : 1, and page :139 - 141

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Original Article :

Chromosome analysis from lymphocyte culture in sexual ambiguity patient

Author :

  1. Ni Wajan Tirthaningsih*1
  2. Susy Kristiani*2
  1. Department of Anatomy and Histology Airlangga University School of Medicine Surabaya
  2. Department of Anatomy and Histology Airlangga University School of Medicine Surabaya

Abstract :

At least three parameters are required for sex assignment, namely: chromosomal sex (karyotype), gonadal sex and genitalia sex. Sexual ambiguity will occur if one of those parameters is not in accordance to the other, which in turn gives rise to many problems, especially social problems. Chromosome analysis had been done to 40 patients with sexual ambiguity, who came to Clinical Genetic Unit of Airlangga University School of Medicine, Dr. Soetomo Hospital Surabaya from January 2004 till May 2005. The results are as follows: 29 patients (72.5 %) with a 46,XY karyotype (which were actually male pseudohermaphroditisms); 9 patients (22.5 %) with a 46,XX karyotype (which were actually female pseudohermaphroditisms); 2 patients (5 %) with a 46,XX karyotype (which were actually true hermaphrodites).

Keyword :

sexual ambiguity, karyotype, pseudohermaphroditisms,


References :

PA Benn,(1986) Chromosome staining and banding techniques Oxford : IRL Press

MA Perle,(1986) Chromosome staining and banding techniques Oxford : IRL Press

DL Capelle,(1972) Analysis review: nature and origin of males with XX sex chromosomes no info : American Journal of Human Genetics

DL Capelle,(1981) The etiology of maleness in XX men no info : Human Genetics

JM Connor,(1997) Essential Medical Genetics London : Blackwell Scientific Publication

M Ferguson-Smith,(1997) Essential Medical Genetics London : Blackwell Scientific Publication

AEH Emery,(1990) Principles and Practice of Medical Genetics New York : Churchill Livingstone

DL Rimoin,(1990) Principles and Practice of Medical Genetics New York : Churchill Livingstone

KL Garver,(1986) Genetic Counseling for Clinicians London : Year Book Medical Publishers Inc

SG Marchese,(1986) Genetic Counseling for Clinicians London : Year Book Medical Publishers Inc

R Lewis,(2003) Hum



Archive Article

Cover Media Content

Volume : 42 / No. : 3 / Pub. : 2006-07
  1. Chromosome Analysis From Lymphocyte Culture In Sexual Ambiguity Patient
  2. Pattern Of Transforming Growth Factor-ß1 (tgf-ß1) Level In Bph And Non-bph Patients
  3. Changes In The Level Of Acth, Cortisol And Lymphocyte T Count After Establishing Diagnosis Of Hiv And Aids
  4. The Effect Of Aerobic Exercise On The Erythrocyte Osmotic Fragility Of The Wistar White Rats
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  11. Urethral Stricture In Female
  12. Review Article And Clinical Experience: Recent Advances In Diabetes Mellitus: 2002-2005. Selected Clinical Aspects, Clinical Experiences, And Possible Applications

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